This article describes the use of Promega's CaspACE™ FITC-VAD-FMK In Situ Marker (Cat.# G7461, G7462)to investigate caspase activation in primary hippocampal cell cultures. The cells were infected with either wildtype or mutant HSV-2 that contains a deletion of the genetic
information encoding the amino terminal domain of the large subunit of ribonucleotide
reductase.
Cell Notes 2, 7–8.
D. Perkins, E.F.R. Pereira, and L. Aurelian