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Promega Corporation

Investigate Signaling Pathways for Less

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  • Use Immediately:
    Pre-designed vectors remove the need to clone and validate an assay.
  • Increased Reporter Gene Expression:
    Codon optimization of synthetic genes for mammalian expression.
  • Reduced Background and Risk of Expression Artifacts:
    Removal of cryptic DNA regulatory elements and transcription factor binding sites.
  • Improved Temporal Response:
    Rapid Response™ technology using destabilized luciferase genes.
  • Easy Transition from Transient to Stable Cells:
    Includes mammalian selectable marker.

16 pathway vectors built in the pGL4.27 Vector

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Save 50% off Select pGL4 Vectors

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Activator / Pathway
cAMP/PKA
Transcription Factor: CREB
Binding Site: Cyclic AMP Response Element
Vector Name: pGL4.29[luc2P/CRE/Hygro]
Use Fisher Scientific Promo Number
PRE8471NP
List Price
$348
 
Pay Only
$174
Calcium/Calcineurin
Transcription Factor: NFAT
Binding Site: Nuclear Factor of Activated T-Cells (NFAT) Response Element
Vector Name: pGL4.30 [luc2P/NFAT-RE/Hygro]
Use Fisher Scientific Promo Number
PRE8481NP
List Price
$348
 
Pay Only
$174
NF-κB
Transcription Factor: NF-κB
Binding Site: Nuclear Factor κB Response Element
Vector Name: pGL4.32 [luc2P/NF-kB-RE/Hygro]
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PRE8491NP
List Price
$348
 
Pay Only
$174
MAP/ERK
Transcription Factor: Elk-1/SRF
Binding Site: Serum Response Element
Vector Name: pGL4.33 [luc2P/SRE/Hygro]
Use Fisher Scientific Promo Number
PRE1340NP
List Price
$348
 
Pay Only
$174
RhoA
Transcription Factor: SRF
Binding Site: Serum Response Factor Response Element
Vector Name: pGL4.34 [luc2P/SRF-RE/Hygro]
Use Fisher Scientific Promo Number
PRE1350NP
List Price
$348
 
Pay Only
$174
Oxidative Stress
Transcription Factor: Nrf2
Binding Site: Antioxidant Response Element (ARE)
Vector Name: pGL4.37 [luc2P/ARE/Hygro]
Use Fisher Scientific Promo Number
PRE3641NP
List Price
$348
 
Pay Only
$174
DNA Damage
Transcription Factor: p53
Binding Site: p53 Response Element (p53 RE)
Vector Name: pGL4.38 [luc2P/p53 RE/Hygro]
Use Fisher Scientific Promo Number
PRE3651NP
List Price
$348
 
Pay Only
$174
Heavy Metal Stress
Transcription Factor: MTF1
Binding Site: Metal Regulatory Element (MRE)
Vector Name: pGL4.40 [luc2P/MRE/Hygro]
Use Fisher Scientific Promo Number
PRE4131NP
List Price
$348
 
Pay Only
$174
Heat Shock
Transcription Factor: HSF1
Binding Site: Heat Shock Element (HSE)
Vector Name: pGL4.41 [luc2P/HSE/Hygro]
Use Fisher Scientific Promo Number
PRE3751NP
List Price
$348
 
Pay Only
$174
Hypoxia
Transcription Factor: Hif1α
Binding Site: Hypoxia Response Element (HRE)
Vector Name: pGL4.42 [luc2P/HRE/Hygro]
Use Fisher Scientific Promo Number
PRE4001NP
List Price
$348
 
Pay Only
$174
Xenobiotic Stress
Transcription Factor: AhR
Binding Site: Xenobiotic Responsive Element (XRE)
Vector Name: pGL4.43 [luc2P/XRE/Hygro]
Use Fisher Scientific Promo Number
PRE4121NP
List Price
$348
 
Pay Only
$174
MAPK/JNK
Transcription Factor: AP1
Binding Site: AP1 Response Element (AP1 RE)
Vector Name: pGL4.44 [luc2P/AP1 RE/Hygro]
Use Fisher Scientific Promo Number
PRE4111NP
List Price
$348
 
Pay Only
$174
INF-α
Transcription Factor: STAT1:STAT2
Binding Site: Interferon-Stimulated Response Element (ISRE)
Vector Name: pGL4.45 [luc2P/ISRE/Hygro]
Use Fisher Scientific Promo Number
PRE4141NP
List Price
$348
 
Pay Only
$174
IL-6
Transcription Factor: STAT3:STAT3
Binding Site: sis-Inducible Element (SIE)
Vector Name: pGL4.47 [luc2P/SIE/Hygro]
Use Fisher Scientific Promo Number
PRE4041NP
List Price
$348
 
Pay Only
$174
TGF-β
Transcription Factor: SMAD3:SMAD4
Binding Site: SMAD Binding Element (SBE)
Vector Name: pGL4.48 [luc2P/SBE/Hygro]
Use Fisher Scientific Promo Number
PRE3671NP
List Price
$348
 
Pay Only
$174
Wnt
Transcription Factor: LEF-TCF
Binding Site: TCF-LEF Response Element (TCF-LEF RE)
Vector Name: pGL4.49 [luc2P/TCF-LEF RE/Hygro]
Use Fisher Scientific Promo Number
PRE4611NP
List Price
$348
 
Pay Only
$174

*Offer expires on December 31, 2013.

You must order the Fisher Scientific Promotion Number as listed above to receive the promotion price or offer listed. No credits or adjustments will be given for orders placed without the specific Fisher Scientific Promotion Number or after an expiration date. Offers cannot be combined with any other special offer, promotion, or price discount. Not valid on any prior orders. No substitutions. These offers are valid in US only and all prices are in US dollars.

Promega reserves the right to change or cancel a promotion at any time or to limit quantities. Promotions are not valid through any Helix System.

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