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Promega Corporation

Maxwell® 16 System Applications

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Personal Automation™ for DNA, RNA and Protein Purification

Application Documents

High-Concentration (>100ng/µl) Genomic DNA From Whole Blood Using the Maxwell® 16 Low Elution Volume Instrument

We developed a novel DNA isolation chemistry with an automated format that allows genomic DNA isolation from whole blood and elution in 50 microliter volumes. This DNA isolation method does not require laborious extraction from buffy coat samples that characterizes most approaches to high-concentration (>100ng/µl) genomic DNA. more…

Maxwell® 16 Tissue and Cell Total RNA LEV Systems

The purification and analysis of targeted RNA is an important technique used to monitor the expression of genetic information. Purified RNA is routinely used as the template in quantitative RT-PCR (qRT-PCR), RT-PCR or cDNA synthesis to monitor dynamic changes in gene expression due to natural or induced challenges. more…

Personal Automation™ for Increased Productivity

Bench scientists and technicians in basic research, clinical diagnostics or forensic laboratories can spend up to one-third of their time and labor on sample preparation, most commonly nucleic acid or recombinant protein extraction and purification. While highly pure biomolecules are critical for successful results, the number of current and backlogged samples, breadth of sample types, and need to improve consistency of results has many laboratories seeking ways to increase sample preparation efficiency without sacrificing quality. more…

Maxwell® 16 Instrument Accessories Increase the Versatility of Your Maxwell® 16 System

The Maxwell® 16 System is comprised of a preprogrammed instrument and prefilled reagent cartridges, and it can process up to 16 samples in about 30 minutes. The Maxwell® 16 Instrument is available in two configurations: standard elution volume (SEV) and low elution volume (LEV; Table 1). The Maxwell® 16 Instrument can be set in the SEV configuration to process larger sample sizes to maximize purified sample yield, or it can be set to the LEV configuration to maximize purified sample concentration. Using the Maxwell® 16 SEV and LEV hardware accessories, you can easily personalize your Maxwell® 16 Instrument to process a wide variety of samples. more…

Maxwell® 16 Tissue and Cell Total RNA LEV Systems

The purification and analysis of targeted RNA is an important technique used to monitor the expression of genetic information. Purified RNA is routinely used as the template in quantitative RT-PCR (qRT-PCR), RT-PCR or cDNA synthesis to monitor dynamic changes in gene expression due to natural or induced challenges. While isolating high-quality RNA provides the foundation for generating experimental results, obtaining high-concentration RNA is especially important given the sensitivity and small input volume requirements of gene-expression applications. more…

The Versatility of the Maxwell® 16 System for Genomic DNA Extraction

Purification and PCR analysis of DNA are critical techniques used to determine genetic strains of plants, to detect mutations or genetic modifications of an organism, or to identify microorganisms present in a sample. DNA purifications are performed repeatedly and routinely for these applications, and purification techniques are often tailored to meet the demands of the sample type. more…

Introducing the Maxwell™ 16 Instrument: A Simple, Robust and Flexible Tool for DNA Purification

Genomic DNA (gDNA) purification is a routine procedure in the modern molecular biology laboratory. Purified DNA is commonly used in genotyping, mapping or gene structure analysis. Currently, scientists use many different methods for gDNA purification across a range of sample types, sizes and throughputs. High-throughput users have increasingly turned to automation to improve productivity. more…

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Scientists at Your Service

Scientists at Your Service

We offer a range of services to help you succeed using Promega technologies. From product training to set up of automated systems and development of custom applications—our scientific support goes beyond the basics.

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