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Promega Corporation

CE-Marked In Vitro Diagnostic Medical Device—Y Chromosome AZF Analysis

The Y Chromosome AZF Analysis System complies with EU Directive 98/79/EC on in vitro diagnostic medical devices. The Y Chromosome AZF Analysis System provides a multiplex PCR-based method to analyze the integrity of the human Y chromosome AZF region. The Y Chromosome AZF Analysis System is to be used as part of a diagnostic workup to characterize male infertility. This information is potentially useful for patients considering in vitro fertilization because deletions in the AZF region of the Y chromosome are passed on to male offspring produced by in vitro fertilization, resulting in infertility.

The Y Chromosome AZ...

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Storage Conditions

Store all components at –20°C. Avoid multiple freeze-thaw cycles.

For product intended use please see Patents & Disclaimers tab.

Example of amplification of male genomic DNA.Figure 1. Example of amplification of male genomic DNA.

Amplification of male genomic DNA (Part# MD115A) (lanes 1, 3, 5, 7, 9), as well as a negative DNA control (lanes 2, 4, 6, 8, 10), for each of the five Multiplex Master Mixes of the Y Chromosome AZF Analysis System.

Patents - Disclaimers

U.S. Pat. No. 6,242,235, Australian Pat. No. 761757, Canadian Pat. No. 2,335,153 and other patents and patents pending.

This product is designed and sold for use in the multiplex PCR process covered by U.S. Pat. No. 5,582,989. A limited license has been granted under the patent to use only this amount of the product to practice the multiplex PCR process and is conveyed to the purchaser by the purchase of this product.

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