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Promega Corporation

VivoGlo™ Caspase 3/7 Substrate (Z-DEVD-Aminoluciferin Sodium Salt)

VivoGlo™ Caspase-3/7 Substrate (Z-DEVD-Aminoluciferin, Sodium Salt) is a firefly luciferase prosubstrate containing the DEVD tetrapeptide sequence recognized by caspase-3 and -7. Upon activation of caspase-3 or -7, the DEVD peptide is cleaved, and the liberated aminoluciferin reacts with luciferase to generate measurable light. Cleavage has been shown in in cellulo and in vivo systems. For mice, activity of a related salt was demonstrated when 10mg of the substrate in 150μl of saline was injected intraperitoneally. Other references suggest that doses as low as 1.5mg per mouse (50mg/kg) can be used. We recomme...

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VivoGlo™ Caspase-3/7 Substrate (Z-DEVD-Aminoluciferin, Sodium Salt)

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VivoGlo™ Caspase-3/7 Substrate (Z-DEVD-Aminoluciferin, Sodium Salt)

 Components

50mg
- P1781 $ 1,074.00 Add to cart

VivoGlo™ Caspase-3/7 Substrate (Z-DEVD-Aminoluciferin, Sodium Salt)

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VivoGlo™ Caspase-3/7 Substrate (Z-DEVD-Aminoluciferin, Sodium Salt)

 Components

5 × 50mg
- P1782 $ 3,740.00 Add to cart


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Storage Conditions

Store at –20°C.

For product intended use please see Patents & Disclaimers tab.

Use Restrictions

P1781, P1782 For Research Use Only. Not for Use in Diagnostic Procedures.

Patents - Disclaimers

P1781, P1782 This product does not convey a license to use recombinant Coleoptera luciferase under U.S. Pat. Nos. 5,583,024, 5,674,713 and 5,700,673. Promega sells licensed Coleoptera luciferase vectors, which may be used in conjunction with this product.

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