Anti-Human p75 pAb

The p75 neurotrophin receptor (p75^NTR), also known as low-affinity NGF receptor (LNGFR) and p75^LNGFR, binds nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4 with varying specificities. p75^NTR plays an important role in neurotrophic factor signaling including neuronal apoptosis. Anti-Human p75 pAb provides a valuable tool for understanding the role of p75^NTR in neuronal death.

Expand to Read More »

The p75 neurotrophin receptor (p75^NTR), also known as low-affinity NGF receptor (LNGFR) and p75^LNGFR, binds nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3 and neurotrophin-4 with varying specificities. p75^NTR plays an important role in neurotrophic factor signaling including neuronal apoptosis. Anti-Human p75 pAb provides a valuable tool for understanding the role of p75^NTR in neuronal death.

Features - Benefits

• Immunogen: Cytoplasmic domain of the human p75 neurotrophin receptor.
• Antibody Form: Purified rabbit IgG; 1mg/ml in PBS containing 50μg/ml gentamicin.
• Specificity: Human, rat, mouse and chicken p75.

Applications

(Suggested working concentration)

• Immunocytochemistry (1–10μg/ml).
• Immunohistochemistry (1–10μg/ml).
• Immunoprecipitation (1–10μg/ml).

Note: This antibody is not recommended for use in Western blot analysis due to potential for cross-reactivity with the fusion tag on the immunogen.

For more information, see the Protocols & Applications Guide.

Notes

Anti-Human p75 pAb is raised against a recombinant fusion protein produced in E. coli.

« Collapse Content