Cell-Based and Biochemical Assays

HDAC-Glo™ 2 Assay

Selectively measure HDAC isozyme 2 activity or inhibition from cell extracts (cell-based assays) or purified enzyme sources (biochemical assays).

HDAC-Glo™ Class IIa Assay

Selectively measure HDAC class IIa activity or inhibition from cell extracts (cell-based assays) or purified enzyme sources (biochemical assays).

HDAC-Glo™ I/II Assays

Measure the relative activity of HDAC class I and II enzymes from cell extracts or purified enzyme sources with these assays and screening systems.

SIRT-Glo™ Assays

Single-reagent-addition, homogeneous, luminescent assays and screening systems that measure the relative activity of the NAD+-dependent histone deacetylase class III enzymes (sirtuins; SIRTs) from purified enzyme sources.

DUB-Glo™ Protease Assay

An easy assay for DUB, SENP or NEDP Activity. Measures activity of deubiquitinating (DUB), deSUMOylating (SENP) and deneddylating (NEDP) proteases.

Featured Resources

Bioluminescent Assays for Detection of Lysine Deacetylase Activities
A Bioluminescent HDAC Assay for Cell-Based Drug Discovery Scientific Poster