We believe this site might serve you best:

United States

English Continue

This country code will remain if no action is taken to change it.

Don't see your country?
Promega Corporation

Cell-Based and Biochemical Assays

More information on CellTiter Glo 2.0

Need Assistance? Chat

Cell based and biochemical assays for epigenetics
Luminescent HDAC, SIRT and Protease Assays

HDAC-Glo™ Assays are used to determine histone deacetylase activity in cell-based or biochemical formats. These flexible, sensitive and selective bioluminescent assays provide a highly predictive, easy-to-use method for accurate and efficient inhibitor profiling.

Featured Products

HDAC-Glo™ 2 Assay

Selectively measure HDAC isozyme 2 activity or inhibition from cell extracts (cell-based assays) or purified enzyme sources (biochemical assays).

HDAC-Glo™ Class IIa Assay

Selectively measure HDAC class IIa activity or inhibition from cell extracts (cell-based assays) or purified enzyme sources (biochemical assays).

HDAC-Glo™ I/II Assays

Measure the relative activity of HDAC class I and II enzymes from cell extracts or purified enzyme sources with these assays and screening systems.

SIRT-Glo™ Assays

Single-reagent-addition, homogeneous, luminescent assays and screening systems that measure the relative activity of the NAD+-dependent histone deacetylase class III enzymes (sirtuins; SIRTs) from purified enzyme sources.

DUB-Glo™ Protease Assay

An easy assay for DUB, SENP or NEDP Activity. Measures activity of deubiquitinating (DUB), deSUMOylating (SENP) and deneddylating (NEDP) proteases.

Featured Resources

pubhub_fr Bioluminescent Assays for Detection of Lysine Deacetylase Activities

An article describing the HDAC-Glo™ I/II and SIRT-Glo™ Assays. The assays can be multiplexed with viability assays to correlate deacetylase inhibition with cellular fate.

posters_fr A Bioluminescent HDAC Assay for Cell-Based Drug Discovery Scientific Poster

Here we describe efforts to define the utility of the HDAC-Glo™ Assay using structurally diverse HDAC inhibitors and various cell lines.

It appears that you have Javascript disabled. Our website requires Javascript to function correctly. For the best browsing experience, please enable Javascript.

Scientists at Your Service

Scientists at Your Service

We offer a range of services to help you succeed using Promega technologies. From product training to set up of automated systems and development of custom applications—our scientific support goes beyond the basics.

Ask us! We are here to help you.