Cell-Based and Biochemical Assays

Featured Products

NanoBRET™ Protein:Protein Interaction Assays

Live-cell protein interaction assays based on Bioluminescent Resonance Energy Transfer (BRET) for protein targets in bromodomain, transcription, and other protein families. Choose from numerous prebuilt assays, or purchase vectors and reagents to build your own assays in convenient  kit format.

HDAC-Glo™ I/II Assays

Measure the relative activity of HDAC class I and II enzymes from cell extracts or purified enzyme sources with these assays and screening systems.

HDAC-Glo™ 2 Assay

Selectively measure HDAC isozyme 2 activity or inhibition from cell extracts (cell-based assays) or purified enzyme sources (biochemical assays).

HDAC-Glo™ Class IIa Assay

Selectively measure HDAC class IIa activity or inhibition from cell extracts (cell-based assays) or purified enzyme sources (biochemical assays).

SIRT-Glo™ Assays

Single-reagent-addition, homogeneous, luminescent assays and screening systems that measure the relative activity of the NAD+-dependent histone deacetylase class III enzymes (sirtuins; SIRTs) from purified enzyme sources.

Featured Resources

Bioluminescent Assays for Detection of Lysine Deacetylase Activities
A Bioluminescent HDAC Assay for Cell-Based Drug Discovery Scientific Poster