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The MagneSil® Genomic, Large Volume System, is designed for scalable, automated genomic DNA isolation from large-volume samples, eliminating laborious centrifugation steps and the use of hazardous organic solvents. The system has been automated on the Tecan Freedom EVO® liquid handler, providing walkaway purification of genomic DNA from a variety of starting materials, including 1–10ml whole blood samples, regardless of sample storage or shipping conditions. The instrument uses only the amount of reagents required to process each sample, maximizing efficiency and value per prep.
The MagneSil® Genom...
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The MagneSil® Genomic, Large Volume System, uses a robust noncentrifugation-based automated method to purify genomic DNA from fresh, frozen or mishandled blood and other samples with similar yields and quality. The system bypasses many of the challenges of traditional centrifugation-based methods by lysing the entire whole blood sample and then directly capturing total genomic DNA from the lysed sample using MagneSil® Paramagnetic Particles (PMPs). The genomic DNA bound to the MagneSil® PMPs is washed to remove contaminants such as heme and cellular proteins, then eluted into an aqueous solution ready for use in downstream applications. There is no need for tedious and lengthy DNA rehydration. The purified genomic DNA is suitable for a variety of downstream applications such as single and multiplex PCR, restriction digestion and real-time PCR.
For more information, see the Protocols & Applications Guide.
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MagneSil® Genomic, Large Volume System
MagneSil® Paramagnetic Particles
eLysis Buffer, Large Volume System
Store at 22–25°C.
For product intended use please see Patents & Disclaimers tab.
A4082 For Research Use Only. Not for Use in Diagnostic Procedures.A4091 For Laboratory Use. Outside of the United States, this product is intended for research use only unless otherwise stated.
A4082 U.S. Pat. Nos. 6,027,945 and 6,368,800, Australian Pat. No. 732756 and other patents and patents pending.
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