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Promega Corporation

Erase-a-Base™ System

The Erase-a-Base™ System is designed for the rapid construction of plasmid or M13 subclones containing progressive unidirectional deletions of any inserted DNA. The system is based on the procedure developed by Henikoff, in which exonuclease III (Exo III) is used to specifically digest insert DNA from a 5´ protruding or blunt end restriction site. The adjacent sequencing primer binding site is protected from digestion by a 4-base 3´ overhang restriction site or by an α-phosphorothioate-filled end.

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  • Prices valid for US customers only


We are sorry, but this product has been discontinued.

For a compatible replacement, contact Technical Service for assistance.

Technical Service
Product Size Conc. Catalog # *List Price Add to Cart
This product is discontinued.

Erase-a-Base™ System (minus vectors & bacterial strain)

1 system
- E5750

Storage Conditions

Store at –20°C.

For product intended use please see Patents & Disclaimers tab.

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