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See All Kinase Enzyme Systems
Recombinant full-length human PAK4 was expressed by baculovirus in Sf9 cells using an N-terminal GST tag. PAK4 is a recently identified member of the p21-activated kinases (PAKs), which have been implicated in the regulation of cell morphology, motility and transformation. These serine/threonine kinases are activated by and are effectors of small GTPases, cdc 42 and Rac. PAK4 belongs to the Group II PAKs that also includes PAK5 and PAK6. PAK4 has been shown to regulate cell morphology and cytoskeletal organization in mammalian cells.
ADP-Glo™ Kinase Assay is a luminescent kinas...
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ADP-Glo™ Kinase Assay is a luminescent kinase assay that measures ADP formed from a kinase reaction; ADP is converted into ATP, which is a substrate in a reaction catalyzed by Ultra-Glo™ Luciferase that produces light. The luminescent signal positively correlates with ADP amount and kinase activity. The assay is well suited for measuring the effects chemical compounds have on the activity of a broad range of purified kinases, making it ideal for both primary screening as well as kinase selectivity profiling. The ADP-Glo™ Kinase Assay can be used to monitor the activity of virtually any ADP-generating enzyme (e.g., kinase or ATPase) using up to 1mM ATP.
Kinase Enzyme System contains:
PAK4 NCBI Database Entry.
Human Kinase Enzyme Systems and Applications.
Kinase Enzyme System manufactured by SignalChem.
Bulk quantities available upon request.
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PAK4 Kinase Enzyme System
ADP-Glo™ Kinase Assay + PAK4 Kinase Enzyme System
ADP-Glo™ Kinase Assay
Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.
For product intended use please see Patents & Disclaimers tab.
V3201, V3202, V9451 For Research Use Only. Not for Use in Diagnostic Procedures.
V9451 U.S. Pat. Nos. 7,083,911, 7,452,663 and 7,732,128 and other patents.
V9451 U.S. Pat. No. 7,700,310 and other patents and patents pending.
V9451 U.S. Pat. Nos. 7,741,067, 8,361,739, 8,603,767 and other patents and patents pending.
V9451 U.S. Pat. Nos. 6,602,677, 7,241,584 and 8,030,017 and other patents and patents pending.
V9451 U.S. Pat. No. 8,183,007 and other patents and patents pending.
V9451 Licensed from Lonza Nottingham Ltd. under U.S. Pat. Nos. 6,599,711 and 6,911,319 and other pending and issued patents.
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