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Promega Corporation

ACK Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant human ACK (110–476) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. ACK is a tyrosine kinase that binds CDC42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of CDC42Hs (1). Overexpression of ACK in cancer cell lines of epithelial origin increases cellular motility and invasiveness. In a mouse model, ACK overexpression enhances the ability of a human breast cancer cell line to metastasize to the lung and increased mortality (2). Ligand stimulation of alpha-3 beta-1 integ...

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  • Prices valid for US customers only
Product Size Conc. Catalog # *List Price QTY Add to Cart

ACK Kinase Enzyme System

10μg
- V4050 $ 406.00 Add to cart

ACK Kinase Enzyme System

1mg
- V6270 $ 5,990.00 Add to cart
ADP-Glo™ Kinase Assay + ACK Kinase Enzyme System 1 each
- V4051 $ 808.00 Add to cart


Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

For product intended use please see Patents & Disclaimers tab.

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