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DNA-Dependent Protein Kinase (DNA-PK) Peptide Substrate is a highly specific substrate for DNA-PK, with the sequence Glu-Pro-Pro-Leu-Ser-Gln-Glu-Ala-Phe-Ala-Asp-Leu-Trp-Lys-Lys. The Km value for this peptide is 760μM. DNA-PK is a nuclear serine/threonine protein kinase that, when activated by DNA, phosphorylates several DNA-binding substrates, including the tumor suppressor protein p53, the simian virus 40 (SV40) large T antigen and several transcription factors (e.g., SP1, OCT-1, c-Fos and serum response factor).
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DNA-Dependent Protein Kinase Peptide Substrate
DNA-Dependent Protein Kinase Substrate
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This product is available through the Promega Helix onsite stocking program in a –20°C Helix Freezer. The program offers numerous convenient solutions to meet your lab's needs. Helix Freezers are available in two sizes: 5.7 cubic ft. or 9.7 cubic ft.
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V5671 For Research Use Only. Not for Use in Diagnostic Procedures.
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