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Promega Corporation

PMA

Phorbol 12-myristate 13-acetate (PMA) is a specific activator of group A (α, βI, βII, γ) and group B (δ, ε, η, θ) Protein Kinase Cs (PKCs) (in the 1–100nM range). Phorbol esters, such as PMA, affect PKCs by mimicking diacylglycerol, a natural ligand and activator of PKCs. PMA is an effective skin irritant and potent tumor promoter in mice. A common alternative name for PMA is 12-O-tetradecanoylphorbol 13-acetate (TPA). The chemical identity and purity of PMA are confirmed by proton NMR.

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PMA

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PMA

 Components

  • PMA

    V117A1 x 5mg
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  • Helix Freezer

This product is available through the Promega Helix onsite stocking program in a –20°C Helix Freezer. The program offers numerous convenient solutions to meet your lab's needs. Helix Freezers are available in two sizes: 5.7 cubic ft. or 9.7 cubic ft.


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5mg
- V1171 $ 134.00 Add to cart


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Reconstitution

Supplied as a dried material. Resuspend 5mg in 1.62ml of DMSO to produce a stock solution of 5mM.

Storage Conditions

Store dried material at –20°C.

For product intended use please see Patents & Disclaimers tab.

Use Restrictions

V1171 For Research Use Only. Not for Use in Diagnostic Procedures.

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