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Promega Corporation

ABL1 (E255K) Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant human ABL1 (E255K) (27–end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion and stress response. Activity of ABL protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene (1). Translocation and head-to-tail fusion of the BCR and ABL1 genes is present in many cases of chronic myelogeneous leukemia (2). The DNA-binding activi...

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ABL1 (E255K) Kinase Enzyme System

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ABL1 (E255K) Kinase Enzyme System

 Components

10μg
- V5098 $ 406.00 Add to cart

ABL1 (E255K) Kinase Enzyme System

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ABL1 (E255K) Kinase Enzyme System

 Components

1mg
- V6572 $ 5,990.00 Add to cart

ADP-Glo™ Kinase Assay + ABL1 (E255K) Kinase Enzyme System

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ADP-Glo™ Kinase Assay + ABL1 (E255K) Kinase Enzyme System

 Components

  • ABL1 (E255K) Kinase Enzyme System

    V50981 x 10μg
  • ADP-Glo™ Kinase Assay

    V91011 x 1,000 assays
1 each
- V5099 $ 808.00 Add to cart


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Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

For product intended use please see Patents & Disclaimers tab.

Use Restrictions

V5098, V6572, V5099 For Research Use Only. Not for Use in Diagnostic Procedures.

Patents - Disclaimers

V5099 U.S. Pat. Nos. 7,083,911, 7,452,663 and 7,732,128 and other patents.

V5099 U.S. Pat. No. 7,700,310 and other patents and patents pending.

V5099 U.S. Pat. Nos. 7,741,067, 8,361,739, 8,603,767 and other patents and patents pending.

V5099 U.S. Pat. Nos. 6,602,677, 7,241,584 and 8,030,017 and other patents and patents pending.

V5099 U.S. Pat. No. 8,183,007 and other patents and patents pending.

V5099 Licensed from Lonza Nottingham Ltd. under U.S. Pat. Nos. 6,599,711 and 6,911,319 and other pending and issued patents.

V5099 The method of recombinant expression of Coleoptera luciferase is covered by U.S. Pat. Nos. 5,583,024, 5,674,713 and 5,700,673.

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