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Promega Corporation

NEK3 Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant full-length human NEK3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. NEK3 is a member of the NEK family of protein kinases that share high amino acid homology with NIMA (never in mitosis gene a). NEK3 mRNA is detected in all the proliferating cell lines with the amount not changing during the cell cycle (1). During Prolactin receptor signaling, VAV2 is phosphorylated and activated by NEK3. Overexpression of NEK3 in Chinese hamster ovary cells increases cytoskeletal re-organization in response to Prolactin while downregulation of NEK3 expression...

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NEK3 Kinase Enzyme System

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NEK3 Kinase Enzyme System

 Components

10μg
- V4500 $ 406.00 Add to cart

NEK3 Kinase Enzyme System

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NEK3 Kinase Enzyme System

 Components

1mg
- V6592 $ 5,990.00 Add to cart

ADP-Glo™ Kinase Assay + NEK3 Kinase Enzyme System

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ADP-Glo™ Kinase Assay + NEK3 Kinase Enzyme System

 Components

  • NEK3 Kinase Enzyme System

    V45001 x 10μg
  • ADP-Glo™ Kinase Assay

    V91011 x 1,000 assays
1 each
- V4501 $ 808.00 Add to cart


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Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

For product intended use please see Patents & Disclaimers tab.

Use Restrictions

V4500, V6592, V4501 For Research Use Only. Not for Use in Diagnostic Procedures.

Patents - Disclaimers

V4501 U.S. Pat. Nos. 7,083,911, 7,452,663 and 7,732,128 and other patents.

V4501 U.S. Pat. No. 7,700,310 and other patents and patents pending.

V4501 U.S. Pat. Nos. 7,741,067, 8,361,739, 8,603,767 and other patents and patents pending.

V4501 U.S. Pat. Nos. 6,602,677, 7,241,584 and 8,030,017 and other patents and patents pending.

V4501 U.S. Pat. No. 8,183,007 and other patents and patents pending.

V4501 Licensed from Lonza Nottingham Ltd. under U.S. Pat. Nos. 6,599,711 and 6,911,319 and other pending and issued patents.

V4501 The method of recombinant expression of Coleoptera luciferase is covered by U.S. Pat. Nos. 5,583,024, 5,674,713 and 5,700,673.

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