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Promega Corporation

SIK Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant human SIK (1–303) was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. SIK is a protein kinase that is involved in regulating AMPK-related kinases (1). SIK may mediate the physiological effects of LKB1, including its tumour suppressor function. SIK is also involved in signaling by various proteins like STRAD, NUAK1, NUAK2, BRSK1, BRSK2, QIK, QSK, SIK, MARK1, MARK2, MARK3, MARK4 and MELK that are related to AMPK. Activation of SIK1 by phosphorylation on Thr322 can lead to an increase in the catalytic activity of sodium/potassium ATPase alph...

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  • Prices valid for US customers only
Product Size Conc. Catalog # *List Price QTY Add to Cart
SIK Kinase Enzyme System 10μg
- V4156 $ 406.00 Add to cart

SIK Kinase Enzyme System

1mg
- V6561 $ 5,990.00 Add to cart
ADP-Glo™ Kinase Assay + SIK Kinase Enzyme System 1 each
- V4157 $ 808.00 Add to cart


Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

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