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Promega Corporation

MELK Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant human MELK (1–340) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. MELK or maternal embryonic leucine zipper kinase is a member of the Snf1/AMPK kinase family. MELK is a key regulator of the proliferation of malignant brain tumors including their stem cells (1). MELK transcript abundance correlates with malignancy grade in human astrocytomas and represents a therapeutic target for the management of the most frequent brain tumors in adult and children. MELK also plays a role in mammary carcinogenesis through inhibition of the pro-apoptotic ...

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Product Size Conc. Catalog # *List Price Order QTY Add to Cart
MELK Kinase Enzyme System
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MELK Kinase Enzyme System  Components

10μg
- V4150 $ 406.00 Add to cart

MELK Kinase Enzyme System

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MELK Kinase Enzyme System

 Components

1mg
- V6447 $ 5,990.00 Add to cart
ADP-Glo™ Kinase Assay + MELK Kinase Enzyme System
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ADP-Glo™ Kinase Assay + MELK Kinase Enzyme System  Components

  • MELK Kinase Enzyme System

    V41501 x 10μg
  • ADP-Glo™ Kinase Assay

    V91011 x 1,000 assays
1 each
- V4151 $ 808.00 Add to cart


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Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

For product intended use please see Patents & Disclaimers tab.

Use Restrictions

V4150, V6447, V4151 For Research Use Only. Not for Use in Diagnostic Procedures.

Patents - Disclaimers

V4151 U.S. Pat. Nos. 7,083,911, 7,452,663 and 7,732,128 and other patents.

V4151 U.S. Pat. No. 7,700,310 and other patents and patents pending.

V4151 U.S. Pat. Nos. 7,741,067, 8,361,739, 8,603,767 and other patents and patents pending.

V4151 U.S. Pat. Nos. 6,602,677, 7,241,584 and 8,030,017 and other patents and patents pending.

V4151 U.S. Pat. No. 8,183,007 and other patents and patents pending.

V4151 Licensed from Lonza Nottingham Ltd. under U.S. Pat. Nos. 6,599,711 and 6,911,319 and other pending and issued patents.

V4151 The method of recombinant expression of Coleoptera luciferase is covered by U.S. Pat. Nos. 5,583,024, 5,674,713 and 5,700,673.

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