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Promega Corporation

ROCK1 Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant human ROCK1 (amino acids 17–535) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. ROCK1 is a ubiquitously expressed serine-threonine kinase that is a downstream target of the small GTPase RhoA. ROCK1 is involved in diverse cellular functions, including smooth muscle contraction, actin cytoskeleton organization, cell adhesion and motility, and gene expression. ROCK1 contributes to the development of cardiac fibrosis and induction of fibrogenic cytokines in cardiomyocytes in response to pathological stimuli. ROCK1 knockout mice exhibit reduced p...

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ROCK1 Kinase Enzyme System

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ROCK1 Kinase Enzyme System

 Components

10μg
- V3411 $ 406.00 Add to cart

ROCK1 Kinase Enzyme System

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ROCK1 Kinase Enzyme System

 Components

1mg
- V3412 $ 5,990.00 Add to cart

ADP-Glo™ Kinase Assay + ROCK1 Kinase Enzyme System

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ADP-Glo™ Kinase Assay + ROCK1 Kinase Enzyme System

 Components

  • ROCK1 Kinase Enzyme System

    V34111 x 10μg
  • ADP-Glo™ Kinase Assay

    V91011 x 1,000 assays
1 each
- V9581 $ 808.00 Add to cart


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Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

For product intended use please see Patents & Disclaimers tab.

Use Restrictions

V3411, V3412, V9581 For Research Use Only. Not for Use in Diagnostic Procedures.

Patents - Disclaimers

V9581 U.S. Pat. Nos. 7,083,911, 7,452,663 and 7,732,128 and other patents.

V9581 U.S. Pat. No. 7,700,310 and other patents and patents pending.

V9581 U.S. Pat. Nos. 7,741,067, 8,361,739, 8,603,767 and other patents and patents pending.

V9581 U.S. Pat. Nos. 6,602,677, 7,241,584 and 8,030,017 and other patents and patents pending.

V9581 U.S. Pat. No. 8,183,007 and other patents and patents pending.

V9581 Licensed from Lonza Nottingham Ltd. under U.S. Pat. Nos. 6,599,711 and 6,911,319 and other pending and issued patents.

V9581 The method of recombinant expression of Coleoptera luciferase is covered by U.S. Pat. Nos. 5,583,024, 5,674,713 and 5,700,673.

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