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Promega Corporation

PDK1 Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant full-length human PDK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. PDK1 (3-phosphoinositide-dependent protein kinase) is activated by the presence of PtdIns(3,4,5)P3 or PtdIns(3,4)P2. PDK1 then activates protein kinase B (PKB), which in turn, inactivates glycogen synthase kinase-3 (GSK3). The phosphorylation of other proteins by PKB and GSK3 is likely to mediate many of the intracellular actions of insulin. Thus, PDK1 plays a key role in mediating many of the actions of the second messenger(s) PtdIns(3,4,5)P3 and/or PtdIns(3,4)P2. The hum...

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  • Prices valid for US customers only
Product Size Conc. Catalog # *List Price QTY Add to Cart

PDK1 Kinase Enzyme System

10μg
- V2761 $ 406.00 Add to cart

PDK1 Kinase Enzyme System

1mg
- V2762 $ 5,990.00 Add to cart

ADP-Glo™ Kinase Assay + PDK1 Kinase Enzyme System

1 each
- V9681 $ 808.00 Add to cart


Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

For product intended use please see Patents & Disclaimers tab.

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