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Promega Corporation

PDK1 Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant full-length human PDK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. PDK1 (3-phosphoinositide-dependent protein kinase) is activated by the presence of PtdIns(3,4,5)P3 or PtdIns(3,4)P2. PDK1 then activates protein kinase B (PKB), which in turn, inactivates glycogen synthase kinase-3 (GSK3). The phosphorylation of other proteins by PKB and GSK3 is likely to mediate many of the intracellular actions of insulin. Thus, PDK1 plays a key role in mediating many of the actions of the second messenger(s) PtdIns(3,4,5)P3 and/or PtdIns(3,4)P2. The hum...

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PDK1 Kinase Enzyme System

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PDK1 Kinase Enzyme System

 Components

10μg
- V2761 $ 406.00 Add to cart

PDK1 Kinase Enzyme System

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PDK1 Kinase Enzyme System

 Components

1mg
- V2762 $ 5,990.00 Add to cart

ADP-Glo™ Kinase Assay + PDK1 Kinase Enzyme System

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ADP-Glo™ Kinase Assay + PDK1 Kinase Enzyme System

 Components

  • PDK1 Kinase Enzyme System

    V27611 x 10μg
  • ADP-Glo™ Kinase Assay

    V91011 x 1,000 assays
1 each
- V9681 $ 808.00 Add to cart


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Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

For product intended use please see Patents & Disclaimers tab.

Use Restrictions

V2761, V2762, V9681 For Research Use Only. Not for Use in Diagnostic Procedures.

Patents - Disclaimers

V9681 U.S. Pat. Nos. 7,083,911, 7,452,663 and 7,732,128 and other patents.

V9681 U.S. Pat. No. 7,700,310 and other patents and patents pending.

V9681 U.S. Pat. No. 7,741,067 and other patents and patents pending.

V9681 U.S. Pat. Nos. 6,602,677, 7,241,584 and 8,030,017 and other patents and patents pending.

V9681 U.S. Pat. No. 8,183,007 and other patents pending.

V9681 Licensed from Lonza Nottingham Ltd. under U.S. Pat. Nos. 6,599,711 and 6,911,319 and other pending and issued patents.

V9681 The method of recombinant expression of Coleoptera luciferase is covered by U.S. Pat. Nos. 5,583,024, 5,674,713 and 5,700,673.

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