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Promega Corporation

SIRT-Glo™ Assays and Screening Systems

The SIRT-Glo™ Assays and Screening Systems are single-reagent-addition, homogeneous, luminescent assays that measure the relative activity of the NAD+-dependent histone deacetylase (HDAC) class III enzymes (sirtuins; SIRTs) from purified enzyme sources. The assays use an acetylated, luminogenic peptide substrate that can be deacetylated by SIRT activities. Deacetylation of the peptide aminoluciferin substrate is measured using a coupled enzymatic system in which a protease in the Developer Reagent cleaves the deacetylated peptide from the aminoluciferin substrate, releasing aminoluciferin, which is quantified in...

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  • Prices valid for US customers only
Product Size Conc. Catalog # *List Price QTY Add to Cart

SIRT-Glo™ Assay

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SIRT-Glo™ Assay

 Components

  • SIRT-Glo™ Substrate

    G644A1 x 1 vial
  • Developer Reagent

    G653A1 x 10μl
  • Nicotinamide

    G654A1 x 30μl
  • SIRT-Glo™ Buffer

    G658A1 x 25ml
10ml
- G6450 $ 436.00 Add to cart

SIRT-Glo™ Assay

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SIRT-Glo™ Assay

 Components

  • SIRT-Glo™ Substrate

    G644A5 x 1 vial
  • Developer Reagent

    G653B1 x 50μl
  • Nicotinamide

    G654A1 x 30μl
  • SIRT-Glo™ Buffer

    G658B1 x 125ml
5 × 10ml
- G6451 $ 1,612.00 Add to cart

SIRT-Glo™ Assay

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SIRT-Glo™ Assay

 Components

  • SIRT-Glo™ Substrate

    G644B1 x 1 vial
  • Developer Reagent

    G653B2 x 50μl
  • SIRT-Glo™ Buffer

    G658B2 x 125ml
100ml
- G6452 $ 2,098.00 Add to cart

SIRT-Glo™ Screening System

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SIRT-Glo™ Screening System

 Components

  • SIRT-Glo™ Substrate

    G644A1 x 1 vial
  • Developer Reagent

    G653A1 x 10μl
  • Nicotinamide

    G654A1 x 30μl
  • HeLa Nuclear Extract

    G657A1 x 10μl
  • SIRT-Glo™ Buffer

    G658A1 x 25ml
10ml
- G6470 $ 464.00 Add to cart

SIRT-Glo™ Screening System

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SIRT-Glo™ Screening System

 Components

  • SIRT-Glo™ Substrate

    G644A5 x 1 vial
  • Developer Reagent

    G653B1 x 50μl
  • Nicotinamide

    G654A1 x 30μl
  • HeLa Nuclear Extract

    G657A1 x 10μl
  • SIRT-Glo™ Buffer

    G658B1 x 125ml
5 × 10ml
- G6471 $ 1,720.00 Add to cart


Available Separately

Product Size Conc. Catalog # *List Price QTY Add to Cart

Nicotinamide

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Nicotinamide

  Components

  • Nicotinamide

    G654A1 x 30μl
30μl
1M G6540 $ 86.00 Add to cart

HeLa Nuclear Extract

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HeLa Nuclear Extract

  Components

  • HeLa Nuclear Extract

    G657A1 x 10μl
10μl
5mg/ml G6570 $ 125.00 Add to cart

SIRT-Glo™ Control Substrate

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SIRT-Glo™ Control Substrate

  Components

  • SIRT-Glo™ Control Substrate

    G646A1 x 35μl
35μl
- G6460 $ 267.00 Add to cart

Storage Conditions

Store the SIRT-Glo™ Assay components and SIRT-Glo™ Control Substrate at –20°C. Store HeLa Nuclear Extract at –70°C.

For product intended use please see Patents & Disclaimers tab.

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Scientists at Your Service

Scientists at Your Service

We offer a range of services to help you succeed using Promega technologies. From product training to set up of automated systems and development of custom applications—our scientific support goes beyond the basics.

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