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Promega Corporation

P450-Glo™ CYP450 Screening Systems

The P450-Glo™ Screening Systems provide a complete set of reagents for performing luminescent cytochrome P450 assays. The systems include a membrane preparation containing recombinant human cytochrome P450 enzyme, a luminogenic cytochrome P450 substrate appropriate for the enzyme, an NADPH Regeneration System, reaction buffer, Luciferin Detection Reagent and Luciferin-Free Water. The membranes are prepared from baculovirus-infected insect cells and contain human cytochrome P450 and P450 reductase (and cytochrome b5 for CYP2C9 and CYP3A4). The P450-Glo™ Screening Systems also contain a membrane fraction dev...

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  • Prices valid for US customers only
Product Size Conc. Catalog # *List Price QTY Add to Cart

P450-Glo™ CYP3A4 Screening System with Luciferin-IPA

1,000 assays
- V9920 $ 990.00 Add to cart

P450-Glo™ CYP3A4 Screening System (Luciferin-PPXE)
DMSO-Tolerant Assay

1,000 assays
- V9910 $ 990.00 Add to cart

P450-Glo™ CYP1A2 Screening System

1,000 assays
- V9770 $ 990.00 Add to cart

P450-Glo™ CYP2C9 Screening System

1,000 assays
- V9790 $ 990.00 Add to cart

P450-Glo™ CYP3A4 Screening System

1,000 assays
- V9800 $ 990.00 Add to cart

P450-Glo™ CYP2C19 Screening System

1,000 assays
- V9880 $ 990.00 Add to cart

P450-Glo™ CYP2D6 Screening System

1,000 assays
- V9890 $ 990.00 Add to cart
P450-Glo™ CYP2B6 Screening System 1,000 assays
- V9781 $ 990.00 Add to cart

Available Separately

Product Size Conc. Catalog # *List Price QTY Add to Cart

NADPH Regeneration System

1,000 assays
- V9510 $ 130.00 Add to cart

Storage Conditions

Store the CYP1A2, CYP2C9 and CYP3A4 membranes at –70°C. Cytochrome P450 may lose activity with repeated freeze-thaw cycles. Avoid multiple freeze-thaw cycles by dispensing the CYP1A2, CYP2C9 and CYP3A4 membranes into single-use aliquots (e.g., 50μl for 96 reactions). Store aliquots at –70°C. All other components can be stored at –20°C or –70°C and protected from light. The reconstituted Luciferin Detection Reagent can be stored at –20°C for up to 3 months. For convenience, the reconstituted Luciferin Detection Reagent can be stored at room temperature (approximately 23°C) without loss of activity for 24 hours or at 4°C for 1 week. Avoid multiple freeze-thaw cycles of all components.

For product intended use please see Patents & Disclaimers tab.

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