Press Releases
Promega StemElite™ ID System Improves Human Cell Line Authentication
MADISON, WISCONSIN (February 19, 2009)
Promega Corporation, a provider of premier cell analysis
tools, announces the launch of StemElite™ ID System, which
is designed to improve and simplify human cell line
authentication in research applications. The new StemElite
ID System allows scientists to quickly and easily validate
the authenticity and purity of their human cell lines prior
to submitting their results for publishing or passing the
cell line to another laboratory. Understanding that
cross-contamination between cell lines is a frequent cause
of scientific misrepresentation, StemElite ID is designed to
give scientists confidence in the integrity of their
results.
The StemElite ID System incorporates the same short tandem
repeat (STR) analysis technology as Promega PowerPlex®
products used for genetic identity by forensics labs world
wide. StemElite ID includes ten human loci for human cell
line authentication and a sensitive marker that specifically
detects contamination with the mouse (mus musculus) DNA. For
stem cell researchers using mouse ‘feeder’ cells this is the
most sensitive method for detection of mouse contamination
in their human stem cell samples.
The kit provides all reagents required for co-amplification
and three color detection of DNA fragments in a single tube
and delivers following benefits:
- Confidence in data - StemElite ID System provides a genetic
profile with a random match probability of 1 in 2.92 x 109.
Cell authentication by genetic profiling has been raised
recently as a critical issue for its grant recipients by US
NIH.
- Detects contamination with mouse DNA - The system
incorporates a sensitive mouse marker. This is specifically
important for human cells lines grown on mouse feeder cells.
- Convenience - Includes a hot start Taq DNA polymerase for convenient room-temperature reaction assembly as well as lane marker standards.
As a supplier of premier cell analysis tools, Promega plans
to continue to make innovative contributions such as
StemElite ID that will fulfill the complex needs of
scientists in the area of human stem cell research.
For more information, visit
Promega Cell Line Authentication
page.
About Promega
Promega Corporation is a leader in
providing innovative solutions and technical support to the life
sciences industry. The company's 2,000 products enable
scientists worldwide to advance their knowledge in genomics,
proteomics, cellular analysis, molecular diagnostics and human
identification. Founded in 1978, the company is headquartered in
Madison, WI, USA with branches in 14 countries and over 50
global distributors. For more information about Promega, visit
www.promega.com
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