Quick Screening Tool Makes
Fast Work of Sorting Crime Samples
Promega Launches PowerPlex® S5 System
MADISON, WISCONSIN (May 20, 2008)
PowerPlex S5 profile obtained from 63pg template DNA. One microliter of the amplification was analyzed on an Applied Biosystems 3130xl Genetic Analyzer with a 3kV, 5-second injection.
Promega Corporation announces a new five loci STR system that
simplifies and accelerates sorting through samples collected at
a crime scene. The new PowerPlex® S5 is designed to help DNA
labs efficiently and effectively process the growing number of
DNA samples that can come from a single crime scene. In these
cases, a quick screening of the samples can be done to identify
contributors and rule out others. A quick screening step offers
advantages over larger multiplexed STR analysis including cost
and labor savings.
The loci in the PowerPlex S5 System provide in a “mini” format
with the largest amplicons less than 250bp. The minimum number
of loci and small size of the amplicons combine to make data
analysis and interpretation of the STR results quick and easy.
PowerPlex S5 also works well with low copy number samples and
touch samples. In many cases, only the smallest amount of DNA
may be available for testing. The robust and careful design of
PowerPlex S5 provides maximum sensitivity with low quantities of
DNA. Reproducible results can be obtained with as little as 50pg
of DNA.
The PowerPlex S5 system comes complete with premixed primer
pairs and internal lane standard in addition to the Taq
DNA polymerase. The simplified system includes a protocol makes
analysis straightforward, and the PCR protocol requires no
ramping.
About Promega
Promega Corporation is a leader in providing innovative solutions and technical support to the life sciences industry. The company's 2,000 products enable scientists worldwide to advance their knowledge in genomics, proteomics, cellular analysis, molecular diagnostics and human identification. Founded in 1978, the company is headquartered in Madison, WI, USA with branches in 14 countries and over 50 global distributors. For more information about Promega, visit
www.promega.com.