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A Complete Solution for Measuring Biological and Cellular
Activities: GloMax™ Luminometers and Bioluminescent Assays
Kevin Kopish, B.S., and Natalie Betz, Ph.D.
Promega Corporation
Beginning with firefly luciferase reporter gene assays, Promega has a long
history of producing assays in which bioluminescence is the output
signal. We have expanded our luminescent technology to include a wide
variety of assays for measuring different biochemical or cellular
activities including apoptosis, cell viability, kinase activity and
toxicology. Here we introduce the GloMax™ Integrated Luminescence
Systems. The GloMax™ Systems are composed of reagents, instruments,
software and protocols all with a single, comprehensive support system.
Because of the excellent sensitivity and broad dynamic range of the
GloMax™ 96 luminometers, these are state-of-the-art, yet easy-to-use
instruments for measuring any luminescent signal. They are ideally
suited to measure bioluminescent assays available from Promega. Here we
describe the use of the GloMax™ Luminometer to measure cell viability
and caspase activity to highlight the integration between
high-performance instrumentation and bioluminescent assays.
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