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Automated Purification of PCR Products Using
MagneSilTM Paramagnetic Particles
By Paula Brisco, M.S., Bob McLaren, Ph.D., Don Creswell, B.S., Pete
Stecha,
B.S. and Randy Hoffman, B.S.
Promega Corporation
We have developed a robust system to purify PCR products from reaction contaminants
using MagneSilTM Paramagnetic Particles (PMPs). MagneSilTM PMPs act
as a "mobile solid phase" to purify PCR products using laboratory robotic
systems. Purified PCR products are ready-to-use in downstream applications, demonstrated
by microarraying and fluorescent DNA sequencing.
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