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The Y Chromosome Deletion Detection System, Version 1.1
Susan Frackman, Ph.D., Marijo Kent, Ph.D. and Angela Ryan,
M.Sc.
Promega Corporation
The identification and analysis of pathology associated with Y chromosome deletions is
an important tool for the study of male infertility. Screening for Y chromosome deletions
has been hampered by a lack of standardized primer sets for sequence tagged sites
(STSs).
The Y Chromosome Deletion Detection System, Version 1.1, offers the opportunity for
standardization using four Multiplex Master Mixes that screen for a total of eighteen
previously identified and mapped STSs. Y chromosome deletions in the regions amplified by
these primers are associated with male infertility.
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