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Improved Non-Radioactive Assay to Measure Cellular Proliferation
or Toxicity: The CellTiter 96® AQueous One Solution Cell
Proliferation Assay
By Terry Riss and Rich Moravec
Promega Corporation
Tetrazolium compounds are an increasingly popular,
non-radioactive alternative for cellular proliferation and cytotoxicity assays. Promega's
CellTiter 96® AQueous One Solution Assay features the tetrazolium
compound MTS*, a more stable and soluble version of previous tetrazolium compounds. MTS
can be directly substituted for a radioisotope in assays to determine cellular
proliferation or death.
*The MTS tetrazolium compound is the subject of U.S. Patent No. 5,185,450
assigned to the University of South Florida, which is licensed exclusively to Promega
Corporation.
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