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Control and Modulation of Neonatal Myocyte Calcium Movements by Cytokines
L. Maximillian Buja and Roger J. Bick
Department of Pathology and Laboratory Medicine
University of Texas Health Science Center-Houston
Houston, Texas 77030
The cytokines IL-1-alpha, IL-1-beta and TNF were found to affect calcium movements
in cardiac cells. These compounds appear to uncouple calcium transport from adenylate
cyclase/beta-adrenergic receptor mechanisms. This ability indicates that cytokines may
influence how cardiac cells adapt or recover from stress and injury.
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