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Luminogenic Enzyme Substrates: The Basis for a New Paradigm in
Assay Design
Poncho L. Meisenheimer1, Martha A.
O’Brien2, and James J. Cali2,
1Promega Biosciences, Inc., 2Promega
Corporation
Luciferin derivatives as luminogenic substrates provide the basis for a
new paradigm in enzyme assay design that brings the advantages of
bioluminescence—superior sensitivity, resistance to interference, and
ease of use—to the enzymology researcher. Here we highlight our wide
selection of bioluminescent enzyme substrates for proteases, metabolic
enzymes and β-galactosidase.
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