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Expanding Applications of Bioluminescence Technology: Predictive
Bioassays for TNFα Biologicals Potency and Dose-Standardization
Studies
Sarah Shultz, Andrew Niles, Jey Cheng and Simon
T.M. Allard
Promega Corporation
Simple and predictive bioassays for potency and dose-standardization are
still sought by the biopharmaceutical industry. Automatable, homogeneous
bioassays are desirable because they can help to streamline this
evaluative process. Implementing straightforward predictive
automation-friendly bioassays as demonstrated in this article allows
effective assessment of anti-TNFα and likely other biologicals for quality control. This article was reprinted in
Promega
Notes 100 with permission from Genetic Engineering News.
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