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DeadEnd™ Colorimetric Apoptosis Detection System for the Analysis
of Retinal Apoptosis
by Caterina Cascio1,4, Domenica Russo2,3, Marco Guarneri5, and
Patrizia Guarneri1*
(*Corresponding author: e-mail to pguarneri@ibs.pa.cnr.it)
1Ist. Biologia dello Sviluppo, 2Lab Elettromicroscopia, Ist.
Metodologia Diagnostica Avanzata, C.N.R, Palermo; 3Sez. Biologia e Genetica,
Dip. Biopatologia e Met. Biomediche, 4Ist. Neuropsichiatria, 5Facoltà
di Medicina e Chirurgia, Università di Palermo, Italy
In this study, the DeadEnd™ Colorimetric TUNEL System (Cat.#
G7130) was used to
identify apoptosis in mammalian retinas (5µm sections) following treatment with NMDA, an
apoptotic trigger. DNA fragmentation is a hallmark of apoptosis, and the DeadEnd™
System uses TUNEL assay for the detection of DNA fragmentation in individual cells or
tissue sections. Immunostaining results are shown.
PDF article (138kb)
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