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Neural Notes

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Anti-VAChT pAb: Marker for Cholinergic Neurons

The purified Anti-Vesicular Acetylcholine Transporter (Anti-VAChT ) pAb (Cat.# G4481) provides researchers with a novel tool to identify cholinergic neurons in the central and peripheral nervous system where the antibody stains fibers and neuronal cell bodies. This antibody is ideal for the study of cholinergic pathophysiology as it relates to understanding various neurodegenerative diseases.

Anti-TrkB In pAb: Antibody Specific for the Intracellular Domain of TrkB Receptor

Anti-TrkB In (Cat.# G1561)is a polyclonal chicken IgY antibody developed using a peptide immunogen representing the intracellular portion of TrkB, amino acids 482-501 (HISNGSN-TPSSSEGGPDAVI). We have tested this antibody in rat and nonhuman primate tissues, as well as in a human melanoma cell line.

Anti-Human Tryptase mAb Biotin: Marker for Neuroimmunological Studies

Promega now offers an antibody for studying the interactions between mast cells and sensory neurons. Anti-Human Tryptase mAb Biotin (Cat.# G3361) is highly specific for human mast cell tryptase, the major protease in human mast cells, and is exquisitely sensitive for detecting and identifying mast cells. This antibody is purified using Protein A and it has been qualified for use in immunohistochemistry, ELISA and Western blot applications with human tissues and fluids.

Donkey Anti-Rabbit IgG (H+L), AP

Promega has qualified this affinity-purified Donkey Anti-Rabbit AP-conjugated secondary antibody (Cat.# V7971) for use with Promega’s Anti-ACTIVE® Antibodies in Western analysis using chemiluminescent and colorimetric detection methods. The antibody exhibits minimal cross-reactivity to goat, mouse and sheep IgG, as well as bovine serum albumin (BSA) and proteins in mammalian cell extracts.

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