Lauren McIntyre¹ and George Carmody^2
1 Health Services Research and Development, Department of Veterans Affairs, VA Medical Center, Durham, NC
² Carleton University, Ottawa, Ontario, Canada

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Testing genetic data for Hardy-Weinberg Equilibrium has traditionally been based on methods for analysis of discrete data. Recently, methods for testing Hardy-Weinberg equilibrium for continuous data have been explored. STR data are neither strictly discrete, nor strictly continuous and thus the challenge is to determine the most appropriate way to test these data for Hardy-Weinberg Equilibrium. In addition, as the testing is motivated by the need to use these data as a basis for computing genotype frequencies, the strategy used to compute genotype frequencies must also be considered when determining an appropriate testing strategy. We present different ways to test STR data for Hardy-Weinberg and discuss some of the consequences of these different approaches.