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Citations

Citations from the peer-review literature of Promega products in novel and interesting applications

Added 21-February-2003 (listings by Article title and Promega product)

  • Inhibition of Ligand-mediated HER2 Activation in Androgen-independent Prostate Cancer.
    ---CellTiter-Glo™ Luminescent Cell Viability Assay
  • Action of a Novel Anticancer Agent, CHS 828, on Mouse Fibroblasts: Increased Sensitivity of Cells Lacking Poly (ADP-Ribose) Polymerase-1.
    ---CellTiter-Glo™ Luminescent Cell Viability Assay
  • Anti-TAR Polyamide Nucleotide Analog Conjugated with a Membrane-Permeating Peptide inhibits Human Immunodefficiency Virus Type 1 Production.
    ---Dual-Luciferase® Reporter Assay System

Added 14-August-2002 (listings by Article title and Promega product)

  • High Prevalence of Decreased Expression of KAI1 Metastasis Suppressor in Human Oral Carcinogenesis.
    ---SV Total RNA Isolation System
  • NEMO/IKKγ-Deficient Mice Model Incontinentia Pigmenti.
    ---CytoTox 96® Non-Radioactive Cytotoxicity Assay
    ---Anti-PARP p85 Fragment pAb
  • SA-PMPs Provide a Choice of Three Affinity-Based Capture and Magnetic Concentration Strategies for Retroviral Vectors.
    ---Streptavidin MagneSphere® Paramagnetic Particles

Added 12-April-2002 (listings by Article title and Promega product)

  • CXCR4-activated astrocyte glutamate release via TNFα: amplification by microglia triggers neurotoxicity.
    ---Anti-ACTIVE® Caspase-3 pAb
    Asymmetric p38 activation in Zebrafish: Its possible role in symmetric and synchronous cleavage.
    ---Anti-ACTIVE® p38 pAb, Rabbit (pTGpY)
  • Single step generation of protein arrays from DNA by cell-free expression and in situ immobilization (PISA method).
    ---TNT® T7 Quick for PCR DNA System
  • Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease.
    ---Emax® ImmunoAssay Systems 
    ---RQ1 DNase
  • Simplified serum- and steroid-free culture conditions for high-throughput viability analysis of primary cultures of cerebellar granule neurons.
    ---CellTiter 96® AQueous One Solution Cell Proliferation Assay
    ---CytoTox 96® Cytotoxicity Assay
  • Coupled transcription and translation within nuclei of mammalian cells.
    ---FluoroTect™ GreenLys in vitro Translation Labeling System
  • TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.
    ---Transforming Growth Factor β1, Human, Natural

Added 11-July-2001

  • Creation of genome-wide protein expression libraries using random activation of gene expression.
    ---pTARGET™ Vector
    ---Reverse Transcriptase
    ---PolyATtract® mRNA Isolation System
  • A hairpin binding site in tobacco plasma membranes mediates activation of the pathogenesis-related gene HIN1 independent of extracellular calcium but dependent on mitogen-activated protein kinase activity.
    ---Anti-ACTIVE® MAPK Antibodies
  • A Drosophila IkappaB kinase complex required for relish cleavage and antibacterial immunity.
    ---RiboMAX™ Large Scale RNA Production System
  • Vasopressin mRNA localization in nerve cells: Characterization of cis-acting elements and trans-acting factors.
    ---RiboMAX™ Large Scale RNA Production System
  • Post-translational disruption of the DF508 cystic fibrosis transmembrane conductance regulator (cftr)-molecular chaperone complex with geldanamycin stabilizes DF508 CFTR in the rabbit reticulocyte lysate.
    ---TNT® T7 Coupled Reticulocyte Lysate System

Added 2-May-2001

  • Reverse transcriptase-polymerase chain reaction validation of 25 "orphan" genes from Escherichia coli K-12 MG1655.
    ---Access RT-PCR System
  • A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection.
    ---TNT® Quick Coupled Transcription/Translation System
  • Phosphorylation status of the SCR homeodomain determines its functional activity: essential role for protein phosphatase 2A,B´.
    ---TNT® Quick Coupled Transcription/Translation System
  • Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90.
    ---CaspACE™ Assay System, Colorimetric

Added 23-Feb-2001

  • Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease.
    ---GDNF Emax® ImmunoAssay System
  • Knocking the NT-4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT-4 and BDNF activities.
    ---BDNF & NT-4 Emax® ImmunoAssay System
  • Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis.
    ---TNT® T7 Coupled Reticulocyte Lysate System
  • b-Arrestin 2: A receptor-regulated MAPK scaffold for the activation of JNK3.
    ---Anti-ACTIVE® JNK pAb

Added 16-Oct-2000

  • Genetic analysis of DNA excreted in urine: a new approach for detecting specific genomic DNA sequences from cells dying in an organism.
    ---Wizard® Plus SV Columns
  • Generation of G-to-A and C-to-U changes in HIV-1 transcripts by RNA editing.
    ---PolyATtract® mRNA System---Access RT-PCR System---pGEM®-T Vector
  • Presenilin 1 suppresses the function of c-Jun homodimers via interaction with QM/Jif-1.
    ---Apoptosis Detection System, Fluorescein---TNT® T7 and T3 Coupled Reticulocyte Lysate System---pCI-neo Mammalian Expression Vector
  • The origin of red algae and the evolution of chloroplasts.
    ---SV Total RNA Isolation System
  • Skeletal myogenic potential of human and mouse neural stem cells.
    SV Total RNA Isolation System---Access RT-PCR System---Anti-b-Galactosidase mAb
  • Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia.
    ---pGEM®-T Easy Vector System

Added 9-June-2000

  • Double-stranded RNA specifically disrupts gene expression during planarian regeneration.
    ---RNA Polymerases/Riboprobe® System
  • Two living species of coelacanths?
    ---Wizard® PCR Preps Purification
  • Inhibition of luciferase expression in transgenic Aedes aegypti mosquitoes by Sindbis virus expression of antisense luciferase RNA.
    ---Luciferase Assay System
  • RGD peptides induce apoptosis by direct caspase-3 activation.
    ---CaspACE™ Assay System, Fluorometric

Added 1-March-2000

  • Regulation of JNK by Src during Drosophila development.
    ---Anti-ACTIVE® JNK pAb
  • Rac1 regulates interleukin 1-induced nuclear factor kappaB activation in an inhibitory protein kappaBalpha-independent manner by enhancing the ability of the p65 subunit to transactivate gene expression.
    ---Wizard® PureFection---Passive Lysis Buffer
  • The MEK pathway is required for stimulation of p21WAF1/CIP1 by transforming growth factor-beta.
    ---MEK Inhibitor U0126
  • MEK inhibitors block BDNF-dependent and -independent expression of GABAA receptor subunit mRNAs in cultured mouse cerebellar granule neurons.
    ---MEK Inhibitor U0126
  • Maturation and specificity of Plasmodium falciparum subtilisin-like protease-1, a malaria merozoite subtilisin-like serine protease.
    ---Reticulocyte Lysate/Canine Pancreatic Microsomal Membranes
  • One-tube fluorogenic reverse transcription-polymerase chain reaction for the quantitation of feline coronaviruses.
    ---Access RT-PCR System

Added 21-Jan-2000

  • Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and –independent mechanisms.
    ---Anti-ACTIVE®/b-Gal Abs
  • Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice.
    ---Anti-ACTIVE® pAb
  • Postnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinases.
    ---DeadEnd™ Apoptosis Assay
  • CFTR chloride channel regulation by an interdomain interaction.
    ---cAMP-Dependent Protein Kinase 
  • Epithelial tumour cell detection and the unsolved problems of nested RT-PCR: a new sensitive one-step method without false positive results.
    ---Access RT-PCR System

Added 2-Dec-1999

  • Functional requirement of p23 and Hsp90 in telomerase complexes. 
    ---TNT® Systems
  • Telomerase RNA function in recombinant Tetrahymena telomerase.
    ---TNT® Systems
  • Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor.
    ---Luciferase Assay

Added 21-Oct-1999

  • Brain-derived neurotrophic factor mediates the anti-apoptotic effect of NMDA in cerebellar granule neurons: signal transduction cascades and site of ethanol action.
    ---BDNF Emax® ImmunoAssay System---Anti-ACTIVE® pAb
  • A simple method to transfer plasmid DNA into neuronal primary cultures: Functional expression of the mGlu5 receptor in cerebellar granule cells.
    ---TransFast™ Reagent
  • Functionally antagonistic interactions between the TrkA and p75 neurotrophin receptors regulate sympathetic neuron growth and target innervation.
    ---BDNF factor and pAb---CellTiter 96® Assay---DeadEnd™  Apoptosis System
  • Insertion of a retrotransposon in Mbp disrupts mRNA splicing and myelination in a new mutant rat.
    ---pGEM®-T Vector---Primer Pair
  • In vitro virus: Bonding of mRNA bearing puromycin at the 3´-terminal end to the C-terminal end of its encoded protein on the ribosome in vitro.
    ---Reticulocyte Lysate---Modifying Enzymes
  • Mechanisms for generating the autonomous cAMP-dependent protein kinase required for long-term facilitation in Aplysia.
    ---Reticulocyte Lysate---TNT® System
  • Fas ligand: A sensor for DNA damage critical in skin cancer etiology.
    ---Apoptosis System
  • Human acyl-CoA:cholesterol acyltransferase-1 in the endoplasmic reticulum contains seven transmembrane domains.
    ---GeneEditor™ Mutation System

Added 20-Sept-1999

  • HMG-1 as a late mediator of endotoxin lethality in mice.
    ---SV RNA & Access RT-PCR Systems
  • Light-dependent sequestration of TIMELESS by CRYPTOCHROME.
    ---DLR™ & b-Gal Enzyme Assays---pRL Vector
  • A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme.
    ---TNT® System
  • CREB binding protein coordinates the function of multiple transcription factors including nuclear factor I to regulate phosphoenolpyruvate carboxykinase (GTP) gene transcription.
    ---CheckMate™ Two-Hybrid System
  • Antisense oligonucleotides directed against the viral RNA polymerase gene enhance survival of mice infected with influenza A.
    ---Tfx™-10 Reagent
  • Functional effect of deletion and mutation of the Escherichia coli ribosomal RNA and tRNA pseudouridine synthase RluA.
    ---Pfu DNA Polymerase