|
Download
article
153kb
pdf? |
|
Use of Pluripotent Stem Cell-Derived Cardiomyocytes to Understand Mechanisms of Cardiotoxic Compounds
Jia-Quang He, Junyi Ma, and Blake Anson, Cellular Dynamics International, Inc.
Human pluripotent stem cell technology has the potential to overcome inefficiencies in early drug screening and clinical testing by
allowing researchers to use human cells that reflect a variety of genetic backgrounds in assays that require minimal sample and
test compound. Here we provide information about current practices and brief examples of the use of pluripotent stem cells in
cytotoxicity testing using assays to detect mechanisms of cytotoxicity, such as apoptosis.
See information about
Stem Cell Reagents and
Cellular Analysis
Reagents from Promega
|
