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Luminogenic Substrates: The Basis for a New Paradigm in Assay Design for Proteases and Cytochrome P450 Enzymes

Poncho L. Meisenheimer, Martha A. O'Brien, and James J. Cali, Promega Biosciences, Inc and Promega Corporation

Luciferin derivatives as luminogenic substrates provide the basis for a new paradigm in enzyme assay design that brings the advantages of bioluminescence—superior sensitivity, resistance to interference, and ease of use—to researchers studying proteases or metabolic enzymes. Here we highlight our wide selection of bioluminescent enzyme substrates for proteases, metabolic enzymes and β-galactosidase.

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Cell Notes 22 (2008) 10–14: Request this issue.
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