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USING PROTEASE BIOMARKERS TO MEASURE VIABILITY AND CYTOTOXICITY
We recently identified two new biomarker profiles for viability and
cytotoxicity that circumvent many historical assay chemistry limitations and greatly facilitate multiplex measurements. These markers have proteolytic activities associated
with cell death or viability and can be measured in multiplex using either a single luminogenic substrate with sequential reads, a luminogenic substrate in combination
with a fluorogenic substrate, or with two different fluorogenic substrates.
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