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New, Sensitive Bioluminescent Caspase-GloŽ 2 and 6 Apoptosis Assays:
Using Inhibitors To Achieve Specificity in Cells
Our new, extremely sensitive, homogeneous luminescent
caspase-2 and -6 apoptosis assays provide unique tools for defining
the function of these elusive caspases. An understanding of
cross-reactivity between caspases, their substrates, and the
various peptide inhibitors is critical for interpreting results
from apoptosis studies. Here we provide details on using the Caspase-GloŽ 2 Assay in cells.
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