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A Complete Solution for Measuring Biological and Cellular
Activities: GloMax™ Luminometers and Promega Bioluminescent Assays
Kevin Kopish, B.S. and Natalie Betz, Ph.D., Promega Corporation
Beginning with firefly luciferase reporter gene assays, Promega
has a long history of producing assays in which bioluminescence is the output
signal. We have expanded our luminescent technology to include a wide variety of
assays for measuring different biochemical or cellular activities including
apoptosis, cell viability, kinase activity and toxicity. Here we introduce the
GloMax
Integrated Luminescence Systems. The GloMax™ Systems are composed of reagents,
instruments, software and protocols all with a single, comprehensive support
system. Because of the excellent sensitivity and broad dynamic range of the
GloMax™ 96 Luminometers, these are state-of-the-art, yet easy-to-use instruments
for measuring any luminescent signal. They are ideally suited
to measure bioluminescent assays available from Promega. Here we describe the
use of the GloMax™ Luminometer to measure cell viability and caspase activity to
highlight the integration between high-performance instrumentation and
bioluminescent assays.
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