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Selecting Cell-Based Assays for Drug Discovery Screening
Terry Riss Ph.D., Rich Moravec, B.S. and Andrew Niles, M.S., Promega Corporation
Promega produces a complete portfolio of homogeneous
"add-mix-measure" assays. Choosing a cell-based screening method requires
understanding the endpoint measured, the correlation with cell viability and the
limitations of the assay chemistries. Here we provide recommendations for
characterizing a model assay system, describe some of the factors to consider
when choosing cell-based assays for automated systems and show examples of
multiplexing cell-based assays.
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