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Characterizing Responses to Treatments Using Homogeneous
Caspase Activity and Cell Viability Assays
by Andrew Niles, M.S., Rich Moravec, B.S., and Terry Riss,
Ph.D., Promega Corporation
Promega now offers a complement of fluorescent and luminescent
methods to measure caspase activities and correlates of cellular health.
Homogeneous caspase assays are available to measure caspase-3/7, caspase-8 and
caspase-9. These caspase assays can be used in parallel with Promega cell
viability assays to provide a more complete picture of how a treatment or
compound affects cell viability. Furthermore, the add-mix-measure format
provides a simple and efficient means to scale the assays for increased volumes
or high-throughput use.
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