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Choosing the Right Cell-Based Assay for Your Research
Terry Riss, Ph.D., Martha O'Brien, Ph.D., and Richard Moravec,
B.S.
Promega Corporation
A variety of methods for measuring in vitro toxicity and apoptosis have been
adapted for use as automated high-throughput screening assays. Choosing the
right assay tool and the appropriate endpoint to measure are essential to
generate meaningful data. We discuss examples of homogeneous in vitro
cytotoxicity and apoptosis assays that measure different endpoints and describe
the considerations for using each assay.
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