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Apoptosis Detection Using the Acumen Explorer™ ADS and
Promega's Anti-PARP p85 Fragment Antibody
by Matthew Cook, Ph.D., Acumen Bioscience, Ltd. and Terry Riss,
Ph.D., Promega Corporation
Accurate detection and quantitation of apoptotic events are key to further
understand cellular mechanisms with a view to discovering novel drugs. This
study describes a method for the immunocytochemical detection of the 85kDa
caspase-cleaved fragment of human PARP (a marker of apoptosis) in HeLa cells
using the Acumen Explorer™ ADS instrument.
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