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| 1. |
Hock, C., Heese, K., Mueller-Spahn, F., Huber, P., Riesen, W., Nitsch, R.M., and Otten, U.
(2000)
Increased CSF levels of nerve growth factor in patients with Alzheimer’s disease.
Neurology
54
,
2009-2011
.
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Notes:
The levels of various nerve growth factors were quantitated in the cerebrospinal fluid from Alzheimer's disease patients, nondemented control subjects, and age-matched patients with major depression. Brain-derived neurotrophic factor, neurotrophin-4, and neurotrophin-3 levels were determined using Promega's BDNF Emax® ImmunoAssay System, NT-4 Emax® ImmunoAssay System, and NT-3 Emax® ImmunoAssay System, respectively.
(0002317) |
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Products: Anti-Human BDNF pAb | Anti-Human NT-3 pAb | BDNF Emax® ImmunoAssay System | NT-3 Emax® ImmunoAssay System |
| 2. |
Liang, F.-Q., Allen, G., Earnest, D.
(2000)
Role of brain-derived neurotrophic factor in the circadian regulation of the suprachiasmatic pacemaker by light
J. Neurosci.
20
,
2978-2987
.
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Notes:
The Anti-BDNF pAb and the Anti-Chicken IgY Alkaline Phosphatase Conjugate were used to produce a 'homebrew' immunoassay. The antibody was used as the detection antibody in a two antibody sandwich assay.
(0000802) |
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Products: Anti-Chicken IgY, AP Conjugate | Anti-Human BDNF pAb |
| 3. |
LeMaster, A.M., Krimm, R.F., Davis, B.M., Noel, T., Forbes, M.E., Johnson, J.E., Albers, K.M.
(1999)
Overexpression of brain-derived neurotrophic factor enhances sensory innervation and selectively increases neuron number.
J. Neurosci.
19
,
5919-5931
.
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Notes:
The BDNF Emax® ImmunoAssay was used to assess the levels of BDNF in various normal and transgenic mouse tissues: skin, trigeminal ganglia, nodose-petrosal ganglia and SCG. Good detail is provided for tissue preparation. (BDNF ELISA)
(0000827) |
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Products: Anti-Human BDNF pAb | BDNF Emax® ImmunoAssay System |
| 4. |
Tandon, P., Yang, Y., Das, K., Holmes, G.L., Stafstrom, C.E.
(1999)
Neuroprotective effects of brain-derived neurotrophic factor in seizures during development.
Neuroscience
91(1)
,
293-303
.
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Notes:
The Anti-Human BDNF pAb was used to produce a 'homebrew' immunoassay. The antibody was used as the detection antibody in a two antibody sandwich assay for BDNF. Extracts of rat hippocampus previously perfused with sense or antisense oligonucleotides to the BDNF cDNA were assayed.
(0000027) |
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Products: Anti-Human BDNF pAb |
| 5. |
Krüttgen, A., Möller, J.C., Heymach, J.V. Jr, and Shooter, E.M.
(1998)
Neurotrophins induce release of neurotrophins by the regulated secretory pathway
Proc. Natl. Acad. Sci. U S A
95
,
9614-9619
.
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Notes:
To examine the regulation of neurotrophin secretion, the release of neurotrophins from PC12 cells transfected with various neurotrophin expression vectors was quantitated. To quantatite BDNF an ELISA was developed by coating the plates with the TrkB-Fc receptor body and detecting with the Anti-Human BDNF pAb and the Anti-Chicken IgY, HRP Conjugate. There was no crossreactivity with NGF, NT-3, and NT-4/5 at 1 µg/ml. The Anti-Human p75 pAb was also used in this study.
(0002359) |
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Products: Anti-Human BDNF pAb | Anti-Human p75 pAb |