The use of DNA-directed RNA interference is expanding rapidly. The references listed below allow for insight into how this technology is
currently being utilized and of its potential.
View ddRNAi References Archive
Updated December 2004
Zhao, X.
et al. (2004) The human histone gene expression regulator HBP/SLBP
is required for histone and DNA synthesis, cell cycle progression and cell
proliferation in mitotic cells. J. Cell. Sci. 117, 6043-6051.
Zang, M-X.
et al. (2004) Cooperative Interaction between the Basic
Helix-loop-helix Transcription Factor dHAND and Myocyte Enhancer Factor 2C
Regulates Myocardial Gene Expression. J. Biol. Chem. 279,
54258-54263.
Rajnish, S.
et al. (2004) Antiviral Effects of Human Immunodeficiency Virus
Type 1-Specific Small Interfering RNAs against Targets Conserved in Select
Neurotropic Viral Strains. J. Virol. 78, 13687–13696.
Alpatov, R.
et al. (2004) Nuclear Speckle-Associated Protein Pnn/DRS Binds to
the Transcriptional Corepressor CtBP and Relieves CtBP- Mediated Repression of
the E-Cadherin. Gene. Mol. Cell. Biol. 24, 10223–10235.
Hua Cheng, H.
et al. (2005) Molecular Mechanism of hTid-1, the Human Homolog
of Drosophila Tumor Suppressor l(2)Tid, in the Regulation of NF-κB
Activity and Suppression of Tumor Growth. Mol. Cell. Biol. 25, 44-59.
Updated October 2004
Gudmundsdottir, K. et al. (2004), DSS1 is required for RAD51
focus formation and genomic stability in mammalian cells. EMBO. Rep.
5, 989 - 993.
Saville, M-K. et al. (2004) Regulation of p53 by the
Ubiquitin-conjugating Enzymes UbcH5B/C in Vivo. J. Biol. Chem.
279, 42169 - 42181.
Seo, S-R. et al. (2004) The novel E3 ubiquitin ligase Tiul1
associates with TGIF to target Smad2 for degradation. EMBO J.
23, 3780 - 3792.
Yang, R. (2004) Papillomavirus-Like Particles Stimulate Murine Bone
Marrow-Derived Dendritic Cells To Produce Alpha Interferon and Th1
Immune Responses via MyD88. J. Virol. 78, 11152 - 11160.
Deora, A-B. et al. (2004) An Annexin 2 Phosphorylation Switch
Mediates p11-dependent Translocation of Annexin 2 to the Cell Surface.
J. Biol. Chem. 279, 43411 - 43418.
Ricci, M-S. et al. (2004) Direct Repression of FLIP Expression by
c-myc Is a Major Determinant of TRAIL Sensitivity. Mol. Cell. Biol.
24, 8541 - 8555.
Arrighi, J-F et al. (2004) Lentivirus-Mediated RNA Interference
of DC-SIGN Expression Inhibits Human Immunodeficiency Virus Transmission
from Dendritic Cells to T Cells. J. Virol. 78, 10848 -
10855.
Buckingham, S. et al. (2004) RNA interference: from model
organisms towards therapy for neural and neuromuscular disorders.
Hum. Mol. Genet. 13, 275 - 288.
Giuliano, K-A. (2004) High-Content Screening with siRNA Optimizes a Cell
Biological Approach to Drug Discovery: Defining the Role of P53
Activation in the Cellular Response to Anticancer Drugs. J. Biomol.
Screen. 9, 557 - 568.
References updated on September 9, 2004
Xu, J. and Liao, K. (2004) Protein Kinase B/AKT 1 Plays a Pivotal Role
in Insulin-like Growth Factor-1 Receptor Signaling Induced 3T3-L1
Adipocyte Differentiation. J. Biol. Chem. 279, 35914 -
35922.
Kim, J-H. et al. (2004) A Cellular RNA-Binding Protein Enhances
Internal Ribosomal Entry Site-Dependent Translation through an
Interaction Downstream of the Hepatitis C Virus Polyprotein Initiation
Codon. Mol. Cell. Biol. 24, 7878 - 7890.
Kajita, M. et al. (2004) Aberrant Expression of the Transcription
Factors Snail and Slug Alters the Response to Genotoxic Stress.
Mol. Cell. Biol. 24, 7559 - 7566.
Nicewonger, J. et al. (2004) Epstein-Barr Virus (EBV) SM Protein
Induces and Recruits Cellular Sp110b To Stabilize mRNAs and Enhance EBV
Lytic Gene Expression. J. Virol. 78, 9412 - 9422.
Janzen, D. and Geballe, A. (2004) The effect of eukaryotic release
factor depletion on translation termination in human cell lines.
Nucl. Acid. Res. 32, 4491 - 4502.
Tanida, I. et al. (2004) HsAtg4B/HsApg4B/Autophagin-1 Cleaves the
Carboxyl Termini of Three Human Atg8 Homologues and Delipidates
Microtubule-associated Protein Light Chain 3- and GABAA
Receptor-associated Protein-Phospholipid Conjugates. J. Biol. Chem.
279, 36268 - 36276.
Miyamoto, S. et al. (2004) Heparin-Binding EGF-Like Growth Factor
Is a Promising Target for Ovarian Cancer Therapy. Cancer Res.
64, 5720 - 5727.
Kemper, J-K. et al. (2004) Role of an mSin3A-Swi/Snf Chromatin
Remodeling Complex in the Feedback Repression of Bile Acid Biosynthesis
by SHP. Mol. Cell. Biol. 24, 7707 - 7719.
Edovitsky, E. et al. (2004) Heparanase Gene Silencing, Tumor
Invasiveness, Angiogenesis, and Metastasis. J. Natl. Cancer. Inst.
96, 1219 - 1230.
References updated on August 13, 2004
Soret, O. et al. (2004) Topoisomerase I-DNA Complexes Contribute to
Arsenic Trioxide-induced Apoptosis. J. Biol. Chem. 297, 33968-33975.
Wang, X. et al. (2004) The Synergistic Effect of Dexamethasone and
All-trans-retinoic Acid on Hepatic Phosphoenolpyruvate Carboxykinase
Gene Expression Involves the Coactivator p300. J. Biol. Chem. 279,
34191-34200.
Mayorga, M. et al. (2004) Bcl-2 Is a Key Factor for Cardiac
Fibroblast Resistance to Programmed Cell Death. J. Biol. Chem. 279, 34882-34889.
Chen, T. et al. (2004) Nucleocytoplasmic Shuttling of JAZ, a New
Cargo Protein for Exportin-5. Mol. Cell. Biol. 24, 6608-6619.
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