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RNAi Mechanism References

 
The recent application of RNA interference in mammalian cell lines has accelerated the process of understanding the basic mechanism of this phenomenon. The references listed provide information regarding the characterization of RNA interference on a cellular level.

View RNAi Mechanism References Archive

References updated October 2004

Sigova, A. et al. (2004) A single Argonaute protein mediates both transcriptional and posttranscriptional silencing in Schizosaccharomyces pombe. Genes & Dev. 18, 2359 - 2367.

References updated September 2004

Kevin V. Morris, et al. (2004) Small Interfering RNA-Induced Transcriptional Gene Silencing in Human Cells. Science. 305, 1289-1292.

Haaften, G-V. et al. (2004) Gene interactions in the DNA damage-response pathway identified by genome-wide RNA-interference analysis of synthetic lethality. Proc. Natl. Acad. Sci. 101, 12992 - 12996.

Fukagawa, T. et al. (2004) Dicer is essential for formation of the heterochromatin structure in vertebrate cells. Nat. Cell. Biol. 6, 784-791.

References updated August 2004

Chicas, A. et al. (2004) RNAi-dependent and RNAi-independent mechanisms contribute to the silencing of RIPed sequences in Neurospora crassa. Nucl. Acid. Res. 24, 6608-6619.

References added July 2004

Thonberg, H. et al. (2004) Characterization of RNA interference in rat PC12 cells: requirement of GERp95. Biochem. Biophys. Res. Commun. 318, 927-34.

Cullen, B-R. et al. (2004) Derivation and function of small interfering RNAs and microRNAs. Virus Res. 102, 3-9.

Murchison, E. and Hannon, G. (2004) miRNAs on the move: miRNA biogenesis and the RNAi machinery. Curr. Opin. Cell Biol. 6, 223-9.