ddRNAi References Archive

References updated on June 11, 2004

Chang, Y. et al. (2004) Inhibition of the Epstein–Barr virus lytic cycle by Zta-targeted RNA interference. J. Gen. Virol. 85, 1371-1379.

Tien, E. et al. (2004) Identification of the CREB-binding Protein/p300-interacting Protein CITED2 as a Peroxisome Proliferator-activated Receptor Coregulator. J. Biol. Chem. 279, 24053-24063.

Benzeno, S. et al. (2004) Cyclin-Dependent Kinase Inhibition by the KLF6 Tumor Suppressor Protein through Interaction with Cyclin D1. Cancer Res. 64, 3885-3891.

Schomber, T. et al. (2004) Gene silencing by lentivirus-mediated delivery of siRNA in human CD34+ cells. Blood 103, 4511-4513.

Larocca, M-C. et al. (2004) AKAP350 Interaction with cdc42 Interacting Protein 4 at the Golgi Apparatus. Mol. Biol. Cell. 15, 2771-2781.

Chesnutt, C. and Niswander, L. (2004) Plasmid-based short-hairpin RNA interference in the chicken embryo. Genesis. 39, 73-78.

Spänkuch, B. et al. (2004) Cancer Inhibition in Nude Mice After Systemic Application of U6 Promoter–Driven Short Hairpin RNAs Against PLK1. J. Natl. Cancer. Inst. 96, 862-872.

References updated on May 21, 2004

Paddison, P. J. et al. (2004) A resource for large-scale RNA-interference-based screens in mammals. Nature 428, 427-431.

Silva, J. et al. (2004) RNA interference microarrays: High-throughput loss-of-function genetics in mammalian cells. Proc. Natl. Acad. Sci. 101, 6548-6552.

Zheng, X. et al. (2004) γ-Catenin contributes to leukemogenesis induced by AML-associated translocation products by increasing the self-renewal of very primitive progenitor cells. Blood. 103, 3535-3543.

Bromberg-White, J. et al. (2004) Delivery of Short Hairpin RNA Sequences by Using a Replication-Competent Avian Retroviral Vector. J. Virology. 78, 4914-4914.

Ryther, R. et al. (2004) GH1 Splicing Is Regulated by Multiple Enhancers Whose Mutation Produces a Dominant-Negative GH Isoform That Can Be Degraded by Allele-Specific Small Interfering RNA (siRNA). Endocrinology. 145, 2988-2996.

Haraguchi, S. et al. (2004) Specific gene silencing in the pre-implantation stage mouse embryo by an siRNA expression vector system. Mol. Reprod. Dev. 68, 17-24.

Vargas, S. et al. (2004) RNA interference, arthropod-borne viruses, and mosquitoes. Virus. Res. 102, 65-74.

Hu, W. Y. et al. RNA interference against retroviruses. Virus. Res. 102, 59-64.

Park, H. S. et al. (2004) Sequential Activation of Phosphatidylinositol 3-Kinase, ßPix, Rac1, and Nox1 in Growth Factor-Induced Production of H2O2. Mol. Cell. Biol. 24, 4384-4398.

References updated on April 24, 2004

Carette, J. et al. (2004) Conditionally Replicating Adenoviruses Expressing Short Hairpin RNAs Silence the Expression of a Target Gene in Cancer Cells. Cancer. Res. 64, 2663 - 2667.

Zhang, Z. et al. (2004) MDM2 Is a Negative Regulator of p21WAF1/CIP1, Independent of p53. J. Biol. Chem. 279, 16000 - 16006.

Schuck, S. et al. (2004) Generation of single and double knockdowns in polarized epithelial cells by retrovirus-mediated RNA interference. Proc. Natl. Acad. Sci. 101, 4912 - 4917.

References added on March 3, 2004

Gunther, S. et al. (2004) VITO-1 is an essential cofactor of TEF1-dependent muscle-specific gene regulation. Nucl. Acids. Res. 32, 791-802.

Lui, Y. et al. (2004) p42, a Novel Cyclin-dependent Kinase-activating Kinase in Mammalian Cells. J. Biol. Chem. 279, 4507-4514.

Blais, V. et al. (2004) RNA Interference Inhibition of Mus81 Reduces Mitotic Recombination in Human Cells. Mol. Biol. Cell. 15, 552-562.

Scott, L. et al. (2004) Invasion of Normal Human Fibroblasts Induced by v-Fos Is Independent of Proliferation, Immortalization, and the Tumor Suppressors p16INK4a and p53. Mol. Cell. Biol. 24, 1540-1559.

Maeda, S. et al. (2004) Endogenous TGF-ß signaling suppresses maturation of osteoblastic mesenchymal cells. EMBO, J. 23, 552-563.

Zhou, H. et al. (2004) Microtubule-Associated Serine/Threonine Kinase-205 kDa and Fc Receptor Control IL-12 p40 Synthesis and NF- B Activation. J. Immunol. 172, 2559-2568.

Gupta, S. et al. (2004) Inducible, reversible, and stable RNA interference in mammalian cells. Proc. Natl. Acad. Sci. 101, 1927-1932.

Kobayashi, N. et al. (2004) Vector-Based in Vivo RNA Interference: Dose- and Time-Dependent Suppression of Transgene Expression. J. Pharmacol. Exp. Ther. 308, 688-693.

Yang, G. et al. (2004) Inhibition of Breast and Ovarian Tumor Growth through Multiple Signaling Pathways by Using Retrovirus-mediated Small Interfering RNA against Her-2/neu Gene Expression. J. Biol. Chem. 279, 4339-4345.

Updated on March 24, 2004

Bernad, R. et al. (2004) Nup358/RanBP2 Attaches to the Nuclear Pore Complex via Association with Nup88 and Nup214/CAN and Plays a Supporting Role in CRM1-Mediated Nuclear Protein Export. Mol. Cell. Biol. 24, 2373-2384.

Storz, P. et al. (2004) Protein Kinase δ Selectively Regulates Protein Kinase D-Dependent Activation of NF- κ in Oxidative Stress Signaling. Mol. Cell. Biol. 24, 2614-2626.

Ainbinder, E. et al. (2004) Elongation Inhibition by DRB Sensitivity-Inducing Factor Is Regulated by the A20 Promoter via a Novel Negative Element and NF- κ. Mol. Cell. Biol. 24, 2444-2454.

Helwani, F. et al. (2004) Cortactin is necessary for E-cadherin–mediated contact formation and actin reorganization. J. Cell. Biol. 164, 899-910.

Xu, J. et al. (2004) TRIP6 Enhances Lysophosphatidic Acid-induced Cell Migration by Interacting with the Lysophosphatidic Acid 2 Receptor. J. Biol. Chem. 279, 10459-10468.

Cozzi, A. et al. (2004) Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin. Blood, 103, 2377-2883.

Wang, L. et al. (2004) Human Checkpoint Protein hRad9 Functions as a Negative Coregulator To Repress Androgen Receptor Transactivation in Prostate Cancer Cells. Mol. Cell. Biol. 24, 2202-2213.

Ishiguro, K. and Xavier, R. (2004) Homer-3 regulates activation of serum response element in T cells via its EVH1 domain. Blood, 103, 22248-2256.

Huang, A. et al. (2004) Functional silencing of hepatic microsomal glucose-6-phosphatase gene expression in vivo by adenovirus-mediated delivery of short hairpin RNA. FEBS Letters 558, 69-73.

Katayama, K. et al. (2004) RNA interfering approach for clarifying the PPARgamma pathway using lentiviral vector expressing short hairpin RNA. FEBS Letters 560, 178-182.

Liu, C. M. et al. (2004) Retrovirus vector-mediated stable gene silencing in human cell. Biochem. Biophys. Res. Comm. 313, 716-720

Nishitsuji, H. et al. (2004) Expression of small hairpin RNA by lentivirus-based vector confers efficient and stable gene-suppression of HIV-1 on human cells including primary non-dividing cells. Microbes Infect. 6, 76-85.

Hannon, G. J. and Conklin, D. S. (2004) RNA interference by short hairpin RNAs expressed in vertebrate cells. Methods Mol. Biol. 257, 255-266.

Tang, F. C. et al. (2004) Stable suppression of gene expression in murine embryonic stem cells by RNAi directed from DNA vector-based short hairpin RNA. Stem Cells 22, 93-99.

Zhang, L. et al. (2004) RNA interference-mediated silencing of the S100A10 gene attenuates plasmin generation and invasiveness of Colo 222 colorectal cancer cells. J. Biol. Chem. 279, 2053-2062.

Updated on January 28, 2004

Garvard, J. et al. (2004) Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways. J. Cell. Sci. 117, 257-270.

Bergamasci, D. et al. (2004) ASPP1 and ASPP2: Common Activators of p53 Family Members. Mol. Cell. Biol. 24, 1341-1350.

Song, X. et al. (2004) Binding of mouse VL30 retrotransposon RNA to PSF protein induces genes repressed by PSF: Effects on steroidogenesis and oncogenesis. Proc. Natl. Acad. Sci. 101, 621-626.

Shin, J. et al. (2004) Short Hairpin RNA System to Inhibit Human p16 in Squamous Cell Carcinoma. Arch. Otolaryngol. Head Neck Surg. 130, 68-73.

Kang, H. et al. (2004) BRG1 Controls the Activity of the Retinoblastoma Protein via Regulation of p21 (CIP1/WAF1/SDI) Mol. Cell. Biol. 24, 1188-1199.

Ho, R.C. et al. (2004) p38 MAPK regulation of glucose transporter expression and glucose uptake in L6 myotubes and mouse skeletal muscle. Am. J. Physiol. Regulatory, Integrative Comp. Physiol. 286, 342-349.

Dame, C. et al. (2004) Hepatic Erythropoietin Gene Regulation by GATA-4. J. Biol. Chem. 279, 2955-2961.

References added on January 14, 2004

Tang, F. C. et al. (2004) Stable Suppression of Gene Expression in Murine Embryonic Stem Cells by RNAi Directed from DNA Vector-Based Short Hairpin RNA. Stem Cell. 22, 93-99.

Fingar, D. et al. (2004) mTOR Controls Cell Cycle Progression through Its Cell Growth Effectors S6K1 and 4E-BP1/Eukaryotic Translation Initiation Factor 4E. Mol. Cell. Biol. 24, 200-216.

Zhang, J. et al. (2004) RNA Interference-mediated Silencing of the S100A10 Gene Attenuates Plasmin Generation and Invasiveness of Colo 222 Colorectal Cancer Cells. J. Biol. Chem. 279, 2053-2069.

Vallier, L. et al. (2004) Enhancing and Diminishing Gene Function in Human Embryonic Stem Cells. Stem Cell. 22, 2-11.

Carpenter, B. et al. (2004) BASP1 Is a Transcriptional Cosuppressor for the Wilms' Tumor Suppressor Protein WT1. Mol. Cell. Biol. 24, 537-549.

Chevient, S. et al. (2004) The Rab-Binding Protein Noc2 Is Associated with Insulin-Containing Secretory Granules and Is Essential for Pancreatic ß-Cell Exocytosis. Mol. Endocrinol. 18, 117-126.

Matsuda, T. and Cepko, C. (2004) Electroporation and RNA interference in the rodent retina in vivo and in vitro. Proc. Natl. Acad. Sci. 101, 16-22.

References added on December 24, 2003

Barbieri, C. et al. (2003), Np63 Expression Is Regulated by the Phosphoinositide 3-Kinase Pathway. J. Biol. Chem. 278, 51408-51414.

Inman, C. and Shore, P. (2003) The Osteoblast Transcription Factor Runx2 Is Expressed in Mammary Epithelial Cells and Mediates osteopontin Expression. J. Biol. Chem. 278, 48684-48689.

Kunigal, S. et al. (2003) Monocyte-expressed urokinase inhibits vascular smooth muscle cell growth by activating Stat1. Blood. 102, 4377-4383.

Xiao, C. et al. (2003) Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis. Genes and Development 17, 2933-2949.

References added on November 25, 2003

Zhang, Y. et al. (2003) CUL-4A stimulates ubiquitylation and degradation of the HOXA9 homeodomain protein. EMBO J. 22, 6057–6067.

Lee, Ming-Ta M. et al. (2003) Inhibition of Human Immunodeficiency Virus Type 1 Replication in Primary Macrophages by Using Tat- or CCR5-Specific Small Interfering RNAs Expressed from a Lentivirus Vector. J. Virol. 77, 11964–11972.

Pusch, O. et al. (2003) Nucleotide sequence homology requirements of HIV-1-specific short hairpin RNA. Nucl. Acids. Res. 31, 6444-6449.

Czauderna, F. et al. (2003) Inducible shRNA expression for application in a prostate cancer mouse model. Nucl. Acids.Res. 31, 127.

Deng, Z. et al. (2003) Telomere Repeat Binding Factors TRF1, TRF2, and hRAP1 Modulate Replication of Epstein-Barr Virus OriP. J. Virol. 77, 11992-12001.

References added on October 31, 2003

Lee, A.W. et al. (2003) XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response. Mol. Cell. Biol. 23, 7748-7459.

Nawrat, B. et. al. (2003) Efficient inhibition of beta-secretase gene expression in HEK293 cells by tRNAVal-driven and CTE-helicase associated hammerhead ribozymes. Eur. J. Biochem. 270, 3962-3970.

Mataraza, J. et al. (2003) IQGAP1 Promotes Cell Motility and Invasion. J. Biol. Chem. 278, 41237-41245.

Xu, L. et al. (2003) Distinct Domain Utilization by Smad3 and Smad4 for Nucleoporin Interaction and Nuclear Import. J. Biol. Chem. 278, 42569-42577.

References added on October 8, 2003

Byun, J. et al. (2003) Efficient and specific repair of sickle ß-globin RNA by trans-splicing ribozymes. RNA. 9, 1245-1263.

Blander, G. et al. (2003) Superoxide Dismutase 1 Knock-down Induces Senescence in Human Fibroblasts. J. Biol. Chem. 278, 38966-38969.

Annicotte, J. S. et al. (2003) Pancreatic-Duodenal Homeobox 1 Regulates Expression of Liver Receptor Homolog 1 during Pancreas Development. Mol. Cell. Biol. 23, 6713-6724.

Boudeau, J. et al. (2003) MO25 α/β interact with STRAD α/β enhancing their ability to bind, activate and localize LKB1 in the cytoplasm. EMBO, J, 22, 5102-5114.

Waselle, L. et al. (2003) Involvement of the Rab27 Binding Protein Slac2c/MyRIP in Insulin Exocytosis. Mol. Cell. Biol. 14, 4103-4113.

References added on September 24, 2003.

Gao, J. et al. (2003) Sulfation of Tyrosine 174 in the Human C3a Receptor Is Essential for Binding of C3a Anaphylatoxin. J. Biol. Chem. 278, 37902-37906.

Trushin, S. et al. (2003) Protein Kinase C (PKC ) Acts Upstream of PKC To Activate I B Kinase and NF- B in T Lymphocytes. Mol. Cell. Bio. 23, 7068-7081.

Annicotte, J.S. et al. (2003) Pancreatic-Duodenal Homeobox 1 Regulates Expression of Liver Receptor Homolog 1 during Pancreas Development. Mol. Cell. Bio. 23, 6713-6724.

Luo, W. et al. (2003) Axin Utilizes Distinct Regions for Competitive MEKK1 and MEKK4 Binding and JNK Activation. J. Biol. Chem. 278, 37451-37458. 

Cen, B. et al. (2003) Megakaryoblastic Leukemia 1, a Potent Transcriptional Coactivator for Serum Response Factor (SRF), Is Required for Serum Induction of SRF Target Genes. Mol. Cell. Biol. 23, 6597-6608.

Bradl, H. et al. (2003) Interaction of Murine Precursor B Cell Receptor with Stroma Cells Is Controlled by the Unique Tail of 5 and Stroma Cell-Associated Heparan Sulfate.
J. Immuno. 171, 2338-2348.

Hingorani, S. et al. (2003 ) Suppression of BRAF(V599E) in Human Melanoma Abrogates Transformation. Cancer Res. 63, 5198-5202.

Garriga, J. et al. (2003) CDK9 is constrictively expressed throughout the cell cycle, and its steady-state expression is independent of SKP2. Mol. Cell. Biol. 23, 5165-5173.

Ishizuka, T. et al. (2003) The N-CoR/Histone Deacetylase 3 complex is required for repression by thyroid hormone receptor. Mol. Cell. Biol. 23, 5122-5131.

Gou, D. et al. (2003) Gene Silencing in mammalian cells by PCR-based short hairpin RNA FEBS 548,113-118. 

Bancio, C. et al. (2003) Activation of CTP:Phosphocholine Cytidylytransferase a expression during the S phase of the cell cycle is mediated by the transcription factor Sp1 J. Biol. Chem. 278, 32457-32464.

Boden, D. et al. (2003) Promoter choice affects the potency of HIV-1 specific RNA interference Nucl. Acid. Res. 31, 5033-5038. 

Kawasaki, H. & Taira, K. Short hairpin type of dsRNAs that are controlled by tRNAVal promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells. Nucleic Acids Res. 31, 700-707 (2003).

Matsukura, S et al. (2003) Establishment of conditional vectors for hairpin siRNA knockdowns Nucl. Acid. Res. 31, e77.

Xia, G.X. et.al. (2003) An enhanced U6 promoter for synthesis of short hairpin RNA. Nucl. Acids. Res. 31, e100.

Wiznerowicz, M. et al. (2003) Conditional Supression of Cellular Genes: Lentivirus Vector-Mediated Drug-Inducible RNA Interference. J.Vir. 77, 8957-8961.

Chen, Y. et al. (2003) Down Regulation of CXCR4 by Inducible Small Interfering RNA Inhibits Breast Cancer Invasion in Vitro. Cancer Res. 63, 4801-4804.

Tomar, R.S. et al. (2003) Use of adeno-associated viral vector for delivery of small interfering RNA. Oncogene 22, 5712-5715.

Yang, G. et al. (2003) Silencing of H-ras gene expression by retrovirus-mediated siRNA decreases transformation efficiency and tumor growth in a model of human ovarian cancer. Oncogene 22, 5694-5701.

Stewart, S. et al. Lentivirus-delivered stable gene silencing by RNAi in primary cells (2003), RNA 9:493-501.

Tiscornia, G. et al. A general method for gene knockdown in mice by using lentiviral vectors expressing small RNA (2003), Proc. Natl. Acad. Sci. 100, 1844-1848.

Kunath, T. et al. Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype (2003) Nat. Biotechnology 21, 559-561.

Carmell, M. et al. Germline transmission of RNAi in mice (2003) Nat. Structural Biol 10, 91-92. 

Wetering, M. et al. Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector (2003) EMBO Reports 4, 609-615.

Miller, V. et al. Allele-specific silencing of dominant disease genes (2003) Proc. Natl. Acad. Sci. 100, 7195-7200.

Zhang, R. et al. AIP1 mediates TNF-a-induced ASK1 activated by facilitating dissociation of ASK1 from inhibitor 14-3-3 (2003) J. Clinical Investigation 111, 1933-1943.

Liu, G. et al. (2003) The Activation Domains, the Proline-rich Domain, and the C-terminal Basic Domain in p53 Are Necessary for Acetylation of Histones on the Proximal p21 Promoter and Interaction with p300/CREB-binding Protein J. Biol. Chem. 278, 17557-17565.

Vojtek, A. et al. Akt Regulates Basic Helix-Loop-Helix Transcription Factor-Coactivator Complex Formation and Activity during Neuronal Differentiation (2003) Mol. Cell. Biol. 23, 4417-4427.

Kawasaki, H. and Taira, K. Short hairpin type of dsRNAs that are controlled by tRNAVal promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells (2003) Nucl. Acid. Res. 31, 700-707.

Zhang, L. et al. Vector-based RNAi, a novel tool for isoform-specific knock-down of VEGF and anti-angiogenesis gene therapy of cancer (2003). Biochem. Biophys. Res. Commun. 303, 1169-1178.

Yokota, T. et al. Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs (2003) EMBO reports 4, 602-608.

Yoshida, T. et al. Myocardin Is a Key Regulator of CArG-Dependent Transcription of Multiple Smooth Muscle Marker Genes (2003) Circulation Research 92, 856-864.

Tiscornia, G. et al. A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA (2003) Proc. Natl. Acad. Sci. 100, 1844-1848.

Dirac, A. and Bernards, R. Reversal of Senescence in Mouse Fibroblasts through Lentiviral Suppression of p53 (2003) J. Biol. Chem. 278, 11731-11734.

Wilson, J. et al. RNA interference blocks gene expression and RNA synthesis from hepatitis C replicons propagated in human liver cells (2003) Proc. Natl. Acad. Sci. 100, 2783-2788.

Czauderna, F. et al. Functional studies of the PI(3)-kinase signalling pathway employing synthetic and expressed siRNA (2003) Nuc. Acid Res. 31, 670-682.

Castanotto, D. et al. Functional siRNA expression from transfected PCR products (2002) RNA 8, 1454-1460.

Sui, G. et al. A DNA vector-based RNAi technology to suppress gene expression in mammalian cells (2002) Proc. Natl. Acad. Sci. 99, 5515-5520.

Yu, J.H. et al. RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells (2002) Proc. Natl. Acad. Sci. 99, 6047-6052.

Brummelkamp, T. et al. A System for Stable Expression of Short Interfering RNAs in Mammalian Cells (2002) Science, 296, 550-553.

Miyagishi, M. and Taira, K. U6 promoter-driven siRNAs with four uridine 3’ overhangs efficiently suppress target gene expression in mammalian cells (2002) Nature Biotechnology 19, 497-500.

Lee, N.S. et al. Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells (2002) Nature Biotechnology 19, 500-505.

Paul, C. et al. Effective expression of small interfering RNA in human cells (2002) Nature Biotechnology 19, 505-508.

Gaudilliere, B. et al. RNA Interference Reveals a Requirement for Myocyte Enhancer Factor 2A in Activity-dependent Neuronal Survival (2002) J. Biol. Chem. 29, 46442-46446.

McManus, M.T. et al. Gene silencing using micro-RNA designed hairpins (2002) RNA 8, 842-850.