Drug Discovery at Promega
New Live-Cell Biosensor Technology for GPCR Studies
The new GloSensor™ cAMP Assay is a 'zero
step' assay for studies on cAMP kinetics.
The assay is ideal for GPCRs that signal
through cAMP. The nonlytic, live-cell assay is the first application of
the patent-pending technology, which features a
genetically engineered form of firefly luciferase. Get
more biologically relevant data directly from living
cells.Go to the GloSensor™ Technology Web page to learn about this exciting new technology.
Featured Applications
Cell Viability Assays
The MultiTox Assays allow you to measure relative numbers of live and dead cells in a population of cells.
Cell Viability resources...Genetic Reporters for Analyte Screening
ONE-Glo™ Luciferase Assay Reagent provides unequaled, robust performance while eliminating
many of the handling inconveniences that may be experienced when using reporter assays,
especially in an HTS environment.
Kinase Screening
Assay virtually any kinase and distinguish between competitive and noncompetitive inhibitors with the Kinase-Glo® Luminescent Kinase Assays. This ATP-based kinase assay can be used with a variety of kinase and substrate combinations and requires no labeled components or antibodies.
Screen for Kinase Modulators in a High-Throughput Format with Promega Kinase Reagents Cell Signaling Resources...Protease Assays
Our line of bioluminescent, homogeneous protease assays provides rapid, simple & sensitive measurements of protease activities directly from the cellular environment. Maximum sensitivity can be reached within 10–30 minutes of reagent addition, making these assays ideal for HTS applications.
Protease Assay Resources...
Contact the Drug Discovery Team
Do you have a screening question or a specific target? Are you in need of a custom substrate? Contact the Drug Discovery Team at Promega.