Drug Discovery at Promega
The New Gold Standard in Kinase Assays
Profile more kinases in house using a single, easy-to-use platform. ADP-Glo™ Kinase Assay delivers unsurpassed sensitivity and can be used with up to 1mM ATP. The assay measures ADP formation, down to 20nM and can be used with any kinase-substrate combination. ADP-Glo™ Assay tolerates a wide range of conditions and can readily replace existing radioactivity-based assay technologies.
Featured Applications
Live-Cell Biosensor Technology for GPCR Studies
The new GloSensor™ cAMP Assay is a 'zero
step' assay for studies on cAMP kinetics.
The assay is ideal for GPCRs that signal
through cAMP. The nonlytic, live-cell assay is the first application of
the patent-pending technology, which features a
genetically engineered form of firefly luciferase. Get
more biologically relevant data directly from living
cells.
Go to the GloSensor™ Technology Web page to learn about this exciting new technology.
Cell Viability Assays
The MultiTox Assays allow you to measure relative numbers of live and dead cells in a population of cells.
Cell Viability resources...
Genetic Reporters for Analyte Screening
ONE-Glo™ Luciferase Assay Reagent provides unequaled, robust performance while eliminating
many of the handling inconveniences that may be experienced when using reporter assays,
especially in an HTS environment.
Easy Assay for DUB, SENP or NEDP Activity
The DUB-Glo™ Protease Assay is a homogeneous bioluminescent assay that measures the activity of deubiquitinating (DUB), deSUMOylating (SENP) and deneddylating (NEDP) proteases. These proteases reverse the protein modification by ubiquitin and ubiquitin-like proteins and thus are integral components in the complex mechanisms of posttranslational protein regulation in eukaryotes.
Read more about the Dub-Glo™ Protease Assay.
Contact the Drug Discovery Team
Do you have a screening question or a specific target? Are you in need of a custom substrate? Contact the Drug Discovery Team at Promega.