Featured Products
Multiplexed Assay to determine Mechanism of Cell Death
The ApoTox-Glo™ Assay is designed to provide predictive mechanism of toxicity determination with a
simple and fast in vitro assay that measures 3 key independent biomarkers for viability, cytotoxicity and
apoptosis in the same sample well of cells.
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Homogeneous Luminescent Caspase Assays
The Caspase-Glo® Assays monitor toxic effects of compounds at high-throughput capacities, or one sample at a time, in as little as
15 minutes.
Caspase-Glo® 2 Assay... Caspase-Glo® 6 Assay... Caspase-Glo® 3/7 Assay... Caspase-Glo® 8 Assay... Caspase-Glo® 9 Assay...
Homogeneous Fluorescent Caspase-3/7 Assay
The Apo-ONE® Homogeneous Caspase-3/7 Assay is a fast, sensitive, fluorescent apoptosis detection system featuring a homogeneous format.
Learn more...Nonhomogeneous Caspase Assays
The CaspACE™ Assay System, Colorimetric, provides a colorimetric substrate and a cell-permeable inhibitor that allow highly sensitive, quantitative measurement of caspase-3 (DEVDase) protease activity, an early regulatory event in the apoptotic cell death process.
Learn more...The CaspACE™ Assay System, Fluorometric, provides fluorogenic substrates and inhibitors that allow highly sensitive, quantitative measurement of both ICE (Caspase-1) and CPP32 (Caspase-3) protease activities. This assay system may be used with purified enzyme preparations or cell extracts and also can be adapted for use in high throughput systems.
Learn more...In Situ Caspase Assay
CaspACE™ FITC-VAD-FMK In Situ Marker is a fluoroisothiocyanate (FITC) conjugate of the cell-permeable caspase inhibitor VAD-FMK. This structure allows delivery of the inhibitor into the cell where it binds to activated caspase, serving as an in situ marker for apoptosis. The bound marker is localized by fluorescence detection.
Learn more...Caspase Inhibitors
Z-VAD-FMK is a cell-permeant pan caspase inhibitor that irreversibly binds to the catalytic site of caspase proteases, inhibiting induction of apoptosis.
Learn more...Ac-DEVD-CHO is an inhibitor of caspase-3/7 (DEVDase) activity.
Learn more...Apoptosis-Related Antibodies
Detect the cleaved form of PARP, active caspase-3 or phosphorylated kinases with proven antibodies for imaging and western blotting applications.
Anti-pS473 Akt pAb... Anti-ACTIVE® Caspase-3 pAb Anti-PARP p85 Fragment pAbLuminescence Detection
GloMax™ Integrated Luminescence Systems are high performance luminometers designed to function seamlessly with Promega luminescence assays. Promega also provides DLReady certification of luminometers compatible with the Dual-Luciferase® Assay.