The webinar "Improved
Luciferase Reporter Assays for Nuclear Receptor
Function" is a specialist
webinar. Specialist webinars address more
specialized topics and are useful for PhD
students and senior scientists.
Nuclear receptors play important roles in many
cellular functions and are a large target class
for drug discovery. Luciferase reporter assays
are frequently used to study nuclear receptor
function because of their wide dynamic range,
low endogenous activity, and ease of use. Recent
improvements to pGL4 luciferase reporter vectors
have further enhanced its utility for research
and drug discovery. We report on the application
of pGL4 improvements to two reporter formats.
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