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The webinar "Improved Luciferase Reporter Assays for Nuclear Receptor Function" is a specialist webinar. Specialist webinars address more specialized topics and are useful for PhD students and senior scientists. Information Nuclear receptors play important roles in many cellular functions and are a large target class for drug discovery. Luciferase reporter assays are frequently used to study nuclear receptor function because of their wide dynamic range, low endogenous activity, and ease of use. Recent improvements to pGL4 luciferase reporter vectors have further enhanced its utility for research and drug discovery. We report on the application of pGL4 improvements to two reporter formats.
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